Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | GAK | O14976 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5010981 | 0.92 | KDM4E (0.34) | ALDH1A1KDM4EHPGDRAB9AGAK | |
| SCHEMBL5014312 | 0.91 | HRH3 (0.37) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL5015616 | 0.88 | ALDH1A1 (0.39) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL5012158 | 0.85 | KDM4E (0.34) | ALDH1A1KDM4EL3MBTL1RAB9AGAA | |
| SCHEMBL5011042 | 0.85 | KDM4E (0.34) | ALDH1A1KDM4EL3MBTL1RAB9AGAA | |
| SCHEMBL5011046 | 0.85 | KDM4E (0.34) | ALDH1A1KDM4EL3MBTL1RAB9AGAA | |
| SCHEMBL5012148 | 0.84 | KDM4E (0.33) | ALDH1A1KDM4ERAB9AHTT | |
| SCHEMBL5012206 | 0.83 | KDM4E (0.33) | ALDH1A1KDM4ERAB9AHTT | |
| SCHEMBL5063593 | 0.83 | KDM4E (0.33) | ALDH1A1KDM4ERAB9AHTT | |
| SCHEMBL5010975 | 0.83 | KDM4E (0.33) | ALDH1A1KDM4ERAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888597-A2 | ANTIBACTERIAL AGENTS | Warner-Lambert Company LLC (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006120563-A2 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2006-11-16 | — | — | WO | disclosed |