Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | CASP1 | P29466 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24079037 | 0.83 | ALDH1A1 (0.48) | ALDH1A1TSHRMAPK1HSD17B10HPGD | |
| SCHEMBL24079127 | 0.82 | BIRC5 (0.49) | ALDH1A1TSHRMAPK1HSD17B10HPGD | |
| SCHEMBL5011003 | 0.81 | MAPK1 (0.65) | ALDH1A1TSHRMAPK1HSD17B10HPGD | |
| SCHEMBL429115 | 0.77 | CYP2A6 (0.81) | ALDH1A1MAPK1HSD17B10TP53CYP2A6 | |
| SCHEMBL29541186 | 0.77 | CYP2A6 (0.81) | ALDH1A1MAPK1HSD17B10TP53CYP2A6 | |
| SCHEMBL5008781 | 0.77 | CYP2A6 (0.81) | ALDH1A1MAPK1HSD17B10TP53CYP2A6 | |
| SCHEMBL15854444 | 0.76 | CYP11B1 (0.54) | ALDH1A1MAPK1HSD17B10TP53CYP2A6 | |
| SCHEMBL16557798 | 0.76 | CYP2A6 (0.58) | ALDH1A1HSD17B10TP53CYP2A6CYP11B1 | |
| SCHEMBL2789064 | 0.76 | CYP2A6 (0.71) | ALDH1A1MAPK1HSD17B10TP53CYP2A6 | |
| SCHEMBL29541373 | 0.75 | CYP2A6 (0.77) | ALDH1A1MAPK1HSD17B10TP53CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207864-A1 | Organosilanes, Process For Production of the Same, and Use Thereof | SHARP KABUSHIKI KAISHA (JP) | 2008-08-28 | — | — | US | disclosed |