Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | TSHR | P16473 | 3/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.65 |
| ▸ | CASP1 | P29466 | 3/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.65 |
| ▸ | CASP7 | P55210 | 2/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14227011 | 0.92 | NPSR1 (0.59) | MAPK1ALDH1A1TSHRHSD17B10CASP1 | |
| SCHEMBL5010994 | 0.81 | ALDH1A1 (0.52) | MAPK1ALDH1A1TSHRHSD17B10CASP1 | |
| Benzo(K)Fluoranthene SCHEMBL175484 | 0.80 | ALDH1A1 (1.00) | MAPK1ALDH1A1TSHRHSD17B10CASP1 | |
| Benzo(K)Fluoranthene SCHEMBL29393074 | 0.80 | ALDH1A1 (1.00) | MAPK1ALDH1A1TSHRHSD17B10CASP1 | |
| SCHEMBL14805276 | 0.79 | NPSR1 (0.44) | MAPK1ALDH1A1TSHRHSD17B10CASP1 | |
| SCHEMBL4853854 | 0.76 | ALDH1A1 (0.90) | MAPK1ALDH1A1TSHRHSD17B10CASP1 | |
| SCHEMBL16026799 | 0.76 | NPSR1 (0.66) | MAPK1ALDH1A1CASP1CASP7NPSR1 | |
| SCHEMBL29709293 | 0.75 | ALDH1A1 (0.58) | MAPK1ALDH1A1TSHRHSD17B10CASP1 | |
| SCHEMBL5011063 | 0.75 | ALDH1A1 (0.58) | MAPK1ALDH1A1TSHRHSD17B10CASP1 | |
| SCHEMBL13854906 | 0.73 | ALDH1A1 (0.55) | MAPK1ALDH1A1TSHRHSD17B10CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207864-A1 | Organosilanes, Process For Production of the Same, and Use Thereof | SHARP KABUSHIKI KAISHA (JP) | 2008-08-28 | — | — | US | disclosed |