Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5010288 | 0.83 | PIK3CD (0.32) | PIK3CD | |
| SCHEMBL5194246 | 0.79 | PIK3CD (0.34) | PIK3CD | |
| SCHEMBL4594988 | 0.79 | PIK3CD (0.34) | PIK3CD | |
| SCHEMBL19873883 | 0.64 | ALDH1A1 (0.39) | — | |
| SCHEMBL6729529 | 0.64 | PIK3CD (0.52) | PIK3CD | |
| SCHEMBL23168321 | 0.63 | CYP2C19 (0.41) | PIK3CD | |
| Bromide SCHEMBL11252078 | 0.63 | PIK3CD (0.33) | PIK3CD | |
| SCHEMBL504094 | 0.63 | ALDH1A1 (0.38) | — | |
| SCHEMBL11889037 | 0.62 | — | — | |
| SCHEMBL29059387 | 0.62 | CYP2D6 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948185-A2 | INHIBITORS OF AKT ACTIVITY | SmithKline Beecham Corporation (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007058852-A2 | INHIBITORS OF AKT ACTIVITY | SMITHKLINE BEECHAM CORPORATION (US) | 2007-05-24 | — | — | WO | disclosed |