Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ACP3 | P15309 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5010784 | 0.89 | TDP1 (0.56) | TDP1CTNNB1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL17435206 | 0.81 | TDP1 (0.70) | TDP1CTNNB1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL3245846 | 0.81 | TDP1 (0.70) | TDP1CTNNB1CYP1A2ACP3MEN1 | |
| SCHEMBL5008796 | 0.81 | TDP1 (0.59) | TDP1CTNNB1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL5013873 | 0.80 | TDP1 (0.58) | TDP1CYP1A2CYP2C19CYP2C9ACP3 | |
| SCHEMBL28007825 | 0.78 | TDP1 (0.56) | TDP1CTNNB1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL35925 | 0.78 | TDP1 (1.00) | TDP1CTNNB1CYP1A2ACP3MEN1 | |
| SCHEMBL29607554 | 0.78 | TDP1 (1.00) | TDP1CTNNB1CYP1A2ACP3MEN1 | |
| SCHEMBL9271599 | 0.78 | TDP1 (0.66) | TDP1CTNNB1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL28358062 | 0.78 | TDP1 (0.66) | TDP1CTNNB1CYP1A2CYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207864-A1 | Organosilanes, Process For Production of the Same, and Use Thereof | SHARP KABUSHIKI KAISHA (JP) | 2008-08-28 | — | — | US | disclosed |
| EP-1641762-A2 | CCK-1 RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-04-05 | — | — | EP | disclosed |
| WO-2005005393-A2 | CCK-1 RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-01-20 | — | — | WO | disclosed |