Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.49 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5011024 | 0.89 | TDP1 (0.63) | TDP1SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL5013873 | 0.89 | TDP1 (0.58) | TDP1SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL27665302 | 0.79 | NR4A1 (0.50) | TDP1SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL8938039 | 0.79 | NR4A1 (0.50) | TDP1SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL10925556 | 0.77 | NR4A1 (0.48) | TDP1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL17435206 | 0.75 | TDP1 (0.70) | TDP1SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL9956288 | 0.75 | TDP1 (0.65) | TDP1SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL7617976 | 0.75 | TDP1 (0.55) | TDP1SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL5008796 | 0.75 | TDP1 (0.59) | TDP1SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL3245846 | 0.75 | TDP1 (0.70) | TDP1SMN1; SMN2MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207864-A1 | Organosilanes, Process For Production of the Same, and Use Thereof | SHARP KABUSHIKI KAISHA (JP) | 2008-08-28 | — | — | US | disclosed |