Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ACP3 | P15309 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5010784 | 0.89 | TDP1 (0.56) | TDP1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL7617976 | 0.81 | TDP1 (0.55) | TDP1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL9956288 | 0.81 | TDP1 (0.65) | TDP1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL5011024 | 0.80 | TDP1 (0.63) | TDP1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL5010785 | 0.80 | NR4A1 (0.53) | TDP1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL5010156 | 0.79 | CHRNB2 (0.52) | TDP1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL17435206 | 0.77 | TDP1 (0.70) | TDP1MEN1KMT2ASMN1; SMN2KDM4E | |
| Naphthoic Acid SCHEMBL10948465 | 0.77 | TDP1 (0.80) | TDP1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL7565966 | 0.75 | TDP1 (0.74) | TDP1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL269372 | 0.75 | TDP1 (0.62) | TDP1MEN1KMT2ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207864-A1 | Organosilanes, Process For Production of the Same, and Use Thereof | SHARP KABUSHIKI KAISHA (JP) | 2008-08-28 | — | — | US | disclosed |