Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 6/20 | 0.34 |
| ▸ | MMP9 | P14780 | 6/20 | 0.34 |
| ▸ | MMP8 | P22894 | 6/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1747950 | 0.72 | CD274 (0.42) | MMP2MMP9MMP8CD274L3MBTL1 | |
| SCHEMBL5009225 | 0.70 | MMP2 (0.36) | MMP2MMP9MMP8SMN1; SMN2L3MBTL1 | |
| SCHEMBL1747957 | 0.68 | POLB (0.42) | MMP2MMP9MMP8CD274 | |
| SCHEMBL5009223 | 0.66 | — | — | |
| Aminobenzoic Acid SCHEMBL18092766 | 0.63 | TSHR (0.46) | SMN1; SMN2MAPTHPGD | |
| Aminobenzoic Acid SCHEMBL367762 | 0.63 | TSHR (0.46) | SMN1; SMN2MAPTHPGD | |
| Aminobenzoic Acid SCHEMBL366997 | 0.63 | TSHR (0.46) | SMN1; SMN2MAPTHPGD | |
| SCHEMBL4569792 | 0.62 | MAPT (0.68) | SMN1; SMN2L3MBTL1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL9981621 | 0.60 | GRM4 (0.44) | — | |
| Propylene Oxide SCHEMBL4772100 | 0.59 | PARP10 (0.49) | L3MBTL1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7423156-B2 | Preparation and use of aryl alkyl acid derivatives for the treatment of obesity | BAYER PHARMACEUTICALS CORPORATION (US) | 2008-09-09 | — | — | US | disclosed |