Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | AR | P10275 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | STK17B | O94768 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29963529 | 1.00 | RET (0.49) | RETKDRCYP19A1ADORA3MAOB | |
| SCHEMBL16376660 | 0.82 | ESR1 (0.55) | RETKDRCYP19A1ADORA3MAOB | |
| SCHEMBL21371327 | 0.79 | CYP19A1 (0.47) | RETKDRCYP19A1ADORA3MAOB | |
| SCHEMBL18885280 | 0.79 | CYP19A1 (0.47) | RETKDRCYP19A1ADORA3MAOB | |
| SCHEMBL3965026 | 0.79 | CYP19A1 (0.47) | RETKDRCYP19A1ADORA3MAOB | |
| SCHEMBL2838579 | 0.78 | RET (0.58) | RETKDRCYP19A1ADORA3MAOB | |
| SCHEMBL24115843 | 0.77 | RET (0.77) | RETKDRCYP19A1ADORA3MAOB | |
| SCHEMBL29843330 | 0.77 | RET (0.77) | RETKDRCYP19A1ADORA3MAOB | |
| SCHEMBL3362960 | 0.77 | RET (0.77) | RETKDRCYP19A1ADORA3MAOB | |
| SCHEMBL29367518 | 0.77 | RET (0.77) | RETKDRCYP19A1ADORA3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106146-B2 | Therapeutic polymers and methods of generation | MEDTRONIC, INC. (US) | 2012-01-31 | — | — | US | claimed |
| US-20110082266-A1 | THERAPEUTIC POLYMERS AND METHODS OF GENERATION | MEDTRONIC, INC. | 2011-04-07 | — | — | US | claimed |
| US-20070050865-A1 | Polynucleotide encoding 2-hydorxyisoflavanone dehydratase and application of the same | NIHON UNIVERSITY (JP) | 2007-03-01 | — | — | US | claimed |
| EP-0710234-A1 | ISOFLAVONE DERIVATIVES | CHINOIN LTD. (HU) | 1996-05-08 | — | — | EP | claimed |
| WO-1995003293-A1 | ISOFLAVONE DERIVATIVES | CHINOIN LTD. (HU) | 1995-02-02 | — | — | WO | claimed |
| EP-3868360-B1 | COMPOSITION FOR INHIBITING ACTIVATION OF MINERALCORTICOID RECEPTOR | AMOREPACIFIC CORP (KR) | 2025-12-10 | — | — | EP | disclosed |
| CN-115109809-B | Midecarin is a biosynthesis method of (2) | 南京中医药大学 | 2025-03-04 | — | — | CN | disclosed |
| US-20240263203-A1 | RECOMBINANT HOST CELLS WITH IMPROVED PRODUCTION OF TETRAKETIDE DERIVATIVES | IPTECTOR ASSETS APS (DK) | 2024-08-08 | — | — | US | disclosed |
| WO-2023230574-A1 | ENGINEERED PHENYLALANINE AMMONIA LYASE AND TYROSINE AMMONIA LYASE ENZYMES FOR PRODUCING AROMATIC COMPOUNDS | GINKGO BIOWORKS, INC. (US) | 2023-11-30 | — | — | WO | disclosed |
| CN-115109809-A | Biosynthesis method of santalin | 南京中医药大学 | 2022-09-27 | — | — | CN | disclosed |
| US-9139853-B2 | Organisms for the production of cyclohexanone | GENOMATICA, INC. (US) | 2015-09-22 | — | — | US | disclosed |
| EP-2885400-A1 | BIOLOGICAL SYNTHESIS OF DIFUNCTIONAL HEXANES AND PENTANES FROM CARBOHYDRATE FEEDSTOCKS | Celexion, LLC (US) | 2015-06-24 | — | — | EP | disclosed |
| WO-2000071736-A1 | ISOFLAVONOID METHYLATION ENZYME | THE SAMUEL ROBERTS NOBLE FOUNDATION, INC. (US) | 2000-11-30 | — | — | WO | disclosed |
| WO-2000053771-A1 | GENETIC MANIPULATION OF ISOFLAVONOIDS | THE SAMUEL ROBERTS NOBLE FOUNDATION, INC. (US) | 2000-09-14 | — | — | WO | disclosed |
| WO-2000044909-A1 | NUCLEIC ACID SEQUENCES ENCODING ISOFLAVONE SYNTHASE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-08-03 | — | — | WO | disclosed |
| EP-0710234-A1 | ISOFLAVONE DERIVATIVES | CHINOIN LTD. (HU) | 1996-05-08 | — | — | EP | disclosed |
| WO-1995003293-A1 | ISOFLAVONE DERIVATIVES | CHINOIN LTD. (HU) | 1995-02-02 | — | — | WO | disclosed |
| US-4166862-A | WEIGHT-GAIN PROMOTERS | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1979-09-04 | — | — | US | disclosed |
| US-4163746-A | ANABOLIC, 5-METHYL-7-ALKOXYISOFLAVONES | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1979-08-07 | — | — | US | disclosed |
| US-3949085-A | Anabolic-weight-gain promoting compositions containing isoflavone derivatives and method using same | CHINOIN GYOGYSZER-ES VEGYESZETI TERMAKEK GYARA RT (HU) | 1976-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110082266-A1 | THERAPEUTIC POLYMERS AND METHODS OF GENERATION | OGFR, OAT, ALK | RET 815/4885KDR 364/4885CYP19A1 3801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.