Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 10/20 | 0.91 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.74 |
| ▸ | CACNA1G | O43497 | 5/20 | 0.74 |
| ▸ | GAA | P10253 | 4/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.74 |
| ▸ | GLA | P06280 | 2/20 | 0.74 |
| ▸ | MAPT | P10636 | 2/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.74 |
| ▸ | HTT | P42858 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8222485 | 0.95 | HTR3A (1.00) | HTR3AALDH1A1CACNA1GGAAHSD17B10 | |
| SCHEMBL5014211 | 0.88 | HTR3A (0.90) | HTR3AALDH1A1CACNA1GGAAHSD17B10 | |
| SCHEMBL5011323 | 0.85 | HTR3A (0.91) | HTR3AALDH1A1CACNA1GGAAHSD17B10 | |
| SCHEMBL8222473 | 0.82 | HTR3A (1.00) | HTR3AALDH1A1CACNA1GGAAHSD17B10 | |
| SCHEMBL8228010 | 0.82 | HTR3A (1.00) | HTR3AALDH1A1CACNA1GGAAHSD17B10 | |
| SCHEMBL8227894 | 0.81 | CACNA1G (1.00) | HTR3AALDH1A1CACNA1GGAAHSD17B10 | |
| SCHEMBL8230075 | 0.80 | HTR3A (1.00) | HTR3AALDH1A1CACNA1GGAAHSD17B10 | |
| SCHEMBL8230064 | 0.80 | HTR3A (1.00) | HTR3AALDH1A1CACNA1GGAAHSD17B10 | |
| SCHEMBL4248735 | 0.80 | HTR3A (0.67) | HTR3AALDH1A1GAAHSD17B10GLA | |
| SCHEMBL4249481 | 0.79 | HTR3A (0.66) | HTR3AALDH1A1GAAHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008007835-A1 | 2,4-QUINAZOLINE DERIVATIVES HAVING ACTIVITY TO T-TYPE CALCIUM CHANNEL AND PREPARATION METHOD THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2008-01-17 | — | — | WO | disclosed |