SCHEMBL5011600

SCHEMBL5011600

C=Cc1ccsn1.C=Cc1ncccn1

nearest known ligand 0.30

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
KMT2A Q03164 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL544254 0.84
SCHEMBL36385 0.74
SCHEMBL15054859 0.74 HDAC8 (0.35) MEN1NPC1RAB9AKMT2AATM
SCHEMBL28547673 0.72 MEN1 (0.56) MEN1NPC1RAB9AKMT2AATM
SCHEMBL31107108 0.72
SCHEMBL11434204 0.67
SCHEMBL872419 0.63 HDAC8 (0.33)
Pyrrole SCHEMBL29071325 0.63
Styrene SCHEMBL27752825 0.63 ALDH1A1 (0.58) MEN1NPC1RAB9AKMT2AATM
SCHEMBL9359592 0.62 MEN1 (0.67) MEN1NPC1RAB9AKMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7351781-B2 Synthesis of vinyl polymers by controlled radical polymerization PPG INDUSTRIES OHIO, INC. (US) 2008-04-01 US disclosed
US-20050131178-A1 Synthesis of vinyl polymers by controlled radical polymerization WHITE DANIELA (US) 2005-06-16 US disclosed