Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | POLA1 | P09884 | 1/20 | 0.59 |
| ▸ | POLD1 | P28340 | 1/20 | 0.59 |
| ▸ | TYMS | P04818 | 4/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12711718 | 1.00 | TK1 (0.64) | TK1POLBPOLA1POLD1TYMS | |
| SCHEMBL13314171 | 1.00 | TK1 (0.64) | TK1POLBPOLA1POLD1TYMS | |
| SCHEMBL151910 | 1.00 | TK1 (0.64) | TK1POLBPOLA1POLD1TYMS | |
| SCHEMBL20906829 | 1.00 | TK1 (0.64) | TK1POLBPOLA1POLD1TYMS | |
| SCHEMBL7839559 | 0.98 | TK1 (0.66) | TK1POLBTYMS | |
| SCHEMBL23701491 | 0.94 | P2RY6 (0.59) | TK1POLBPOLA1POLD1TYMS | |
| SCHEMBL285181 | 0.90 | TK1 (0.71) | TK1TYMS | |
| SCHEMBL9416368 | 0.90 | TK1 (0.71) | TK1TYMS | |
| SCHEMBL24412668 | 0.89 | POLB (0.60) | TK1POLBPOLA1POLD1TYMS | |
| SCHEMBL6462543 | 0.89 | POLB (0.62) | POLBPOLA1POLD1TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3230524-B2 | — | — | 2001-11-19 | — | — | JP | claimed |
| EP-0447442-B1 | METHOD FOR POLYMERASE ACTIVITY DETERMINATION | KAELLANDER CLAS FREDRIK RUNESS (SE) | 1994-09-21 | — | — | EP | claimed |
| EP-0447442-A1 | METHOD FOR POLYMERASE ACTIVITY DETERMINATION. | KAELLANDER CLAS FREDRIK RUNESS (SE) | 1991-09-25 | — | — | EP | claimed |
| WO-1990006373-A1 | METHOD FOR POLYMERASE ACTIVITY DETERMINATION | KAELLANDER CLAS FREDRIK RUNESS (SE) | 1990-06-14 | — | — | WO | claimed |
| WO-1990006320-A1 | SUBSTRATE FOR POLYMERASE ACTIVITY DETERMINATION | KAELLANDER CLAS FREDRIK RUNESS (SE) | 1990-06-14 | — | — | WO | claimed |
| US-4474748-A | ANTIBIOTICS, FUNGICIDES, ANTISEPTICS | JOHNSON & JOHNSON (US) | 1984-10-02 | — | — | US | claimed |
| EP-1889910-A2 | Systematic evolution of ligands by exponential enrichment: photoselection of nucleic acid ligands and solution selex | SomaLogic, Inc. (US) | 2008-02-20 | — | — | EP | disclosed |
| EP-0736105-B1 | SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENT: PHOTOSELECTION OF NUCLEIC ACID LIGANDS | SOMALOGIC INC (US) | 2007-11-21 | — | — | EP | disclosed |
| US-20040132067-A1 | Systematic evolution of ligands by exponential enrichment: photoselection of nucleic acid ligands and solution selex | SOMALOGIC, INC. | 2004-07-08 | — | — | US | disclosed |
| US-6482594-B2 | Made by exposing nucleic acid candidate sequences having photoreactive groups to the target molecule, irradiating complexes formed to crosslink, and separating the crosslinked complexes and amplifying to give the ligands | SOMALOGIC, INC. | 2002-11-19 | — | — | US | disclosed |
| US-20020106652-A1 | Systematic evolution of ligands by exponential enrichment: photoselection of nucleic acid ligands and solution selex | SOMALOGIC, INC. | 2002-08-08 | — | — | US | disclosed |
| US-6291184-B1 | DETECTING TARGET MOLECULES IN A BIOLOGICAL SUBSTANCE ASSOCIATED WITH DISEASES BY EXPOSING SUBSTANCE TO A NUCLEIC ACID LIGAND THAT PHOTOCROSSLINKS TO A TARGET MOLECULE; IRRADIATING THE SUBSTANCE CONTAINING LIGAND, DETECT COMPLEXES | SOMALOGIC, INC. | 2001-09-18 | — | — | US | disclosed |
| US-6001577-A | SCREENING FOR LIGANDS ASSOCIATED WITH A DISEASE BY DETECTING LIGAND THAT PHOTOCROSSLINKS TO TARGET WITH PHOTOREACTIVE GROUPS FROM CANDIDATE MIXTURE, REMOVING ANY NUCLEIC ACIDS WITH AFFINITIES NOT ASSOCIATED WITH DISEASE, AND AMPLIFYING | NEXSTAR PHARMACEUTICALS, INC. (US) | 1999-12-14 | — | — | US | disclosed |
| WO-1990006373-A1 | METHOD FOR POLYMERASE ACTIVITY DETERMINATION | KAELLANDER CLAS FREDRIK RUNESS (SE) | 1990-06-14 | — | — | WO | disclosed |
| WO-1990006320-A1 | SUBSTRATE FOR POLYMERASE ACTIVITY DETERMINATION | KAELLANDER CLAS FREDRIK RUNESS (SE) | 1990-06-14 | — | — | WO | disclosed |
| US-4474748-A | ANTIBIOTICS, FUNGICIDES, ANTISEPTICS | JOHNSON & JOHNSON (US) | 1984-10-02 | — | — | US | disclosed |
| US-4321257-A | Potentiated medicaments | JOHNSON & JOHNSON (US) | 1982-03-23 | — | — | US | disclosed |
| US-4197318-A | CYCLOHEXYL SUBSTITUTED ALKANOLS AS POTENTIATORS | JOHNSON & JOHNSON (US) | 1980-04-08 | — | — | US | disclosed |
| US-4091090-A | PENETRANT ACCELERATOR COMPRISING CYCLOHEXYL-SUBSTITUTED ALKANOLS | JOHNSON & JOHNSON (US) | 1978-05-23 | — | — | US | disclosed |
| US-4006218-A | MICROBIOCIDE | JOHNSON & JOHNSON (US) | 1977-02-01 | — | — | US | disclosed |