Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | POLA1 | P09884 | 1/20 | 0.57 |
| ▸ | POLD1 | P28340 | 1/20 | 0.57 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.57 |
| ▸ | TK1 | P04183 | 1/20 | 0.56 |
| ▸ | TYMS | P04818 | 2/20 | 0.54 |
| ▸ | DTYMK | P23919 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12711718 | 0.94 | TK1 (0.64) | POLBPOLA1POLD1TK1TYMS | |
| SCHEMBL151910 | 0.94 | TK1 (0.64) | POLBPOLA1POLD1TK1TYMS | |
| SCHEMBL13314171 | 0.94 | TK1 (0.64) | POLBPOLA1POLD1TK1TYMS | |
| SCHEMBL20906829 | 0.94 | TK1 (0.64) | POLBPOLA1POLD1TK1TYMS | |
| SCHEMBL5011746 | 0.94 | TK1 (0.64) | POLBPOLA1POLD1TK1TYMS | |
| SCHEMBL7839559 | 0.92 | TK1 (0.66) | POLBTK1TYMS | |
| SCHEMBL8371071 | 0.86 | POLB (0.62) | POLBPOLA1POLD1TYMS | |
| SCHEMBL24412668 | 0.86 | POLB (0.60) | P2RY6POLBPOLA1POLD1P2RY14 | |
| SCHEMBL1763106 | 0.86 | POLB (0.62) | POLBPOLA1POLD1TYMS | |
| SCHEMBL26779534 | 0.86 | POLB (0.62) | POLBPOLA1POLD1TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250215037-A1 | ELECTROCHEMICALLY-CLEAVABLE LINKERS | MICROSOFT TECHNOLOGY LICENSING, LLC | 2025-07-03 | — | — | US | disclosed |
| US-12281134-B2 | Electrochemically-cleavable linkers | MICROSOFT TECHNOLOGY LICENSING, LLC (US) | 2025-04-22 | — | — | US | disclosed |
| US-20250115635-A1 | LINKER STRUCTURES WITH MINIMAL SCAR FOR ENZYMATIC SYNTHESIS | MICROSOFT TECHNOLOGY LICENSING, LLC | 2025-04-10 | — | — | US | disclosed |
| US-12215121-B2 | Linker structures with minimal scar for enzymatic synthesis | MICROSOFT TECHNOLOGY LICENSING, LLC (US) | 2025-02-04 | — | — | US | disclosed |
| US-20230151047-A1 | LINKER STRUCTURES WITH MINIMAL SCAR FOR ENZYMATIC SYNTHESIS | MICROSOFT TECHNOLOGY LICENSING, LLC | 2023-05-18 | — | — | US | disclosed |
| US-11591361-B2 | Linker structures with minimal scar for enzymatic synthesis | MICROSOFT TECHNOLOGY LICENSING, LLC (US) | 2023-02-28 | — | — | US | disclosed |
| US-20220204544-A1 | LINKER STRUCTURES WITH MINIMAL SCAR FOR ENZYMATIC SYNTHESIS | MICROSOFT TECHNOLOGY LICENSING, LLC. | 2022-06-30 | — | — | US | disclosed |
| US-20210238577-A1 | ELECTROCHEMICALLY-CLEAVABLE LINKERS | MICROSOFT TECHNOLOGY LICENSING, LLC. | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220204544-A1 | LINKER STRUCTURES WITH MINIMAL SCAR FOR ENZYMATIC SYNTHESIS | RNGTT, MMP1, UNG | P2RY6 4399/4885POLB 98/4885POLA1 245/4885 |
| US-20230151047-A1 | LINKER STRUCTURES WITH MINIMAL SCAR FOR ENZYMATIC SYNTHESIS | RNGTT, MMP1, UNG | P2RY6 4399/4885POLB 98/4885POLA1 245/4885 |
| US-20250115635-A1 | LINKER STRUCTURES WITH MINIMAL SCAR FOR ENZYMATIC SYNTHESIS | RNGTT, MMP1, UNG | P2RY6 4399/4885POLB 98/4885POLA1 245/4885 |
| US-20250215037-A1 | ELECTROCHEMICALLY-CLEAVABLE LINKERS | RNGTT, DNPEP, DTYMK | P2RY6 3707/4885POLB 17/4885POLA1 152/4885 |
| US-12281134-B2 | Electrochemically-cleavable linkers | RNGTT, DNPEP, DTYMK | P2RY6 3707/4885POLB 17/4885POLA1 152/4885 |
| US-11591361-B2 | Linker structures with minimal scar for enzymatic synthesis | RNGTT, MMP1, UNG | P2RY6 4399/4885POLB 98/4885POLA1 245/4885 |
| US-12215121-B2 | Linker structures with minimal scar for enzymatic synthesis | RNGTT, MMP1, UNG | P2RY6 4399/4885POLB 98/4885POLA1 245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.