Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2094354 | 0.82 | RIPK1 (0.33) | RIPK1 | |
| SCHEMBL2093180 | 0.79 | — | — | |
| SCHEMBL2092301 | 0.79 | RIPK1 (0.38) | RIPK1 | |
| SCHEMBL933217 | 0.73 | — | — | |
| SCHEMBL2095816 | 0.71 | S1PR1 (0.33) | — | |
| SCHEMBL2093113 | 0.70 | PYCR1 (0.44) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2098322 | 0.70 | PYCR1 (0.48) | ALDH1A1 | |
| SCHEMBL2097209 | 0.69 | PYCR1 (0.50) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2089879 | 0.68 | PYCR1 (0.47) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL17604503 | 0.68 | HRH3 (0.34) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |