Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ6 | P48051 | 8/20 | 0.48 |
| ▸ | KCNJ3 | P48549 | 8/20 | 0.48 |
| ▸ | KCNJ5 | P48544 | 6/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | CRACR2A | Q9BSW2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5005238 | 0.99 | KCNJ6 (0.49) | KCNJ6KCNJ3KCNJ5ADORA1GFER | |
| SCHEMBL5012103 | 0.89 | ALDH1A1 (0.46) | KCNJ6KCNJ3KCNJ5GFERCRACR2A | |
| SCHEMBL3975958 | 0.86 | KCNJ6 (0.46) | KCNJ6KCNJ3KCNJ5ADORA1CRACR2A | |
| SCHEMBL3860022 | 0.85 | KCNJ6 (0.46) | KCNJ6KCNJ3KCNJ5ADORA1CRACR2A | |
| SCHEMBL27637083 | 0.85 | KCNJ6 (0.42) | KCNJ6KCNJ3KCNJ5GFERMAPT | |
| SCHEMBL3975494 | 0.84 | KCNJ6 (0.46) | KCNJ6KCNJ3KCNJ5CRACR2AMAPT | |
| SCHEMBL27637170 | 0.84 | KCNJ6 (0.43) | KCNJ6KCNJ3KCNJ5GFERMAPT | |
| SCHEMBL3979959 | 0.83 | KCNJ6 (0.46) | KCNJ6KCNJ3KCNJ5CRACR2AMAPT | |
| SCHEMBL5008517 | 0.82 | KCNJ6 (0.50) | KCNJ6KCNJ3KCNJ5ADORA1GFER | |
| SCHEMBL3974589 | 0.82 | KCNJ6 (0.47) | KCNJ6KCNJ3KCNJ5CRACR2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080064734-A1 | Anilinopyrazole derivatives useful for the treatment of diabetes | BAYER PHARMACEUTICALS CORPORATION (US) | 2008-03-13 | — | — | US | disclosed |
| US-7265144-B2 | Anilinopyrazole derivatives useful for the treatment of diabetes | BAYER PHARMACEUTICALS CORPORATION (US) | 2007-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064734-A1 | Anilinopyrazole derivatives useful for the treatment of diabetes | IAPP, GLP1R, GPR119 | KCNJ6 1526/4885KCNJ3 636/4885KCNJ5 785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.