SCHEMBL5012068

SCHEMBL5012068

C=CCOC(O)CCOC(=O)C(=C)C

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ THRB P10828 1/20 0.42
▸ TSHR P16473 3/20 0.41
▸ TDP1 Q9NUW8 2/20 0.36
▸ ALDH1A1 P00352 3/20 0.33
▸ POLB P06746 1/20 0.33
▸ APEX1 P27695 1/20 0.33
▸ HTT P42858 1/20 0.33
▸ USP2 O75604 1/20 0.31
▸ CYP3A4 P08684 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ HPGD P15428 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15901831 0.81 THRB (0.55) THRBTSHRTDP1ALDH1A1POLB
SCHEMBL15901806 0.81 THRB (0.48) THRBTSHRTDP1ALDH1A1POLB
SCHEMBL665302 0.79 THRB (0.53) THRBTSHRTDP1ALDH1A1POLB
SCHEMBL4900588 0.78 THRB (0.48) THRBTSHRTDP1ALDH1A1POLB
SCHEMBL25309314 0.77 THRB (0.42) THRBTSHRTDP1ALDH1A1POLB
SCHEMBL9696561 0.77 THRB (0.57) THRBTSHRTDP1ALDH1A1POLB
Ethylene SCHEMBL5680057 0.75 THRB (0.55) THRBTSHRTDP1ALDH1A1POLB
Acrylamide SCHEMBL8431378 0.75 THRB (0.43) THRBTSHRTDP1ALDH1A1POLB
SCHEMBL28357449 0.75 THRB (0.46) THRBTSHRTDP1ALDH1A1POLB
SCHEMBL22017 0.74 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1963402-A2 PROCESS FOR THE PRODUCTION OF MONODISPERSE AND NARROW DISPERSE MONOFUNCTIONAL SILICONES Johnson and Johnson Vision Care, Inc. (US) 2008-09-03 — — EP claimed
US-20060229423-A1 Process for the production of monodisperse and narrow disperse monofunctional silicones JOHNSON & JOHNSON VISION CARE, INC. 2006-10-12 — — US claimed
WO-2006102050-A2 PROCESS FOR THE PRODUCTION OF MONODISPERSE AND NARROW DISPERSE MONOFUNCTIONAL SILICONES JOHNSON & JOHNSON VISION CARE, INC. (US) 2006-09-28 — — WO claimed
US-12545803-B2 Coating agent, resin member, and production method therefor KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) 2026-02-10 — — US disclosed
US-20230407127-A1 COATING AGENT, RESIN MEMBER, AND PRODUCTION METHOD THEREFOR KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) 2023-12-21 — — US disclosed
WO-2022102732-A1 COATING AGENT, RESINOUS MEMBER, AND PRODUCTION METHOD THEREFOR 株式会社豊田自動織機 2022-05-19 — — WO disclosed
EP-1963402-A2 PROCESS FOR THE PRODUCTION OF MONODISPERSE AND NARROW DISPERSE MONOFUNCTIONAL SILICONES Johnson and Johnson Vision Care, Inc. (US) 2008-09-03 — — EP disclosed
US-20060229423-A1 Process for the production of monodisperse and narrow disperse monofunctional silicones JOHNSON & JOHNSON VISION CARE, INC. 2006-10-12 — — US disclosed
WO-2006102050-A2 PROCESS FOR THE PRODUCTION OF MONODISPERSE AND NARROW DISPERSE MONOFUNCTIONAL SILICONES JOHNSON & JOHNSON VISION CARE, INC. (US) 2006-09-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12545803-B2 Coating agent, resin member, and production method therefor SEM1, CDH1, NOTUM THRB 3386/4885TSHR 4269/4885TDP1 4251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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