Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ6 | P48051 | 7/20 | 0.53 |
| ▸ | KCNJ5 | P48544 | 7/20 | 0.53 |
| ▸ | KCNJ3 | P48549 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.45 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.45 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HCK | P08631 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5005347 | 0.85 | KCNJ6 (0.48) | KCNJ6KCNJ5KCNJ3MAPTMAPK12 | |
| SCHEMBL5007721 | 0.81 | MAPK14 (0.55) | MAPTMAPK12MAPK14MAPK13MAPK11 | |
| SCHEMBL5010620 | 0.81 | MAPT (0.51) | MAPTGFERTAS2R14FTOADORA1 | |
| SCHEMBL3305188 | 0.74 | ALDH1A1 (0.55) | MAPTGFERALDH1A1HPGDHSD17B10 | |
| SCHEMBL3974751 | 0.73 | KCNJ6 (0.47) | KCNJ6KCNJ5KCNJ3MAPTALDH1A1 | |
| SCHEMBL5007754 | 0.73 | ADORA1 (0.52) | MAPTGFERFTOADORA1ALDH1A1 | |
| SCHEMBL5005515 | 0.73 | MAPK14 (0.54) | MAPTMAPK12MAPK14MAPK13MAPK11 | |
| SCHEMBL5008768 | 0.73 | MAPK14 (0.53) | MAPTMAPK12MAPK14MAPK13MAPK11 | |
| SCHEMBL5010659 | 0.72 | MAPK14 (0.64) | MAPTMAPK12MAPK14MAPK13MAPK11 | |
| SCHEMBL5011998 | 0.72 | MAPT (0.59) | MAPTGFERADORA1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080064734-A1 | Anilinopyrazole derivatives useful for the treatment of diabetes | BAYER PHARMACEUTICALS CORPORATION (US) | 2008-03-13 | — | — | US | disclosed |
| US-7265144-B2 | Anilinopyrazole derivatives useful for the treatment of diabetes | BAYER PHARMACEUTICALS CORPORATION (US) | 2007-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064734-A1 | Anilinopyrazole derivatives useful for the treatment of diabetes | IAPP, GLP1R, GPR119 | KCNJ6 1526/4885KCNJ5 785/4885KCNJ3 636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.