Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.34 |
| ▸ | GAK | O14976 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5012752 | 0.83 | KDM4E (0.34) | KDM4EHTTGAKHPGDCYP2C19 | |
| SCHEMBL4508573 | 0.78 | KDM4E (0.42) | KDM4EHTTPDE3BPDE3AERN1 | |
| SCHEMBL5015663 | 0.78 | GSK3B (0.36) | KDM4EHTTPDE3BPDE3AGAK | |
| SCHEMBL3075477 | 0.74 | KDM4E (0.39) | KDM4EHTTPDE3BPDE3AALDH1A1 | |
| SCHEMBL4505828 | 0.74 | HTT (0.39) | KDM4EHTTPDE3BPDE3AALDH1A1 | |
| SCHEMBL3066876 | 0.71 | KDM4E (0.36) | KDM4EHTTPDE3BPDE3AALDH1A1 | |
| SCHEMBL12726451 | 0.71 | TSHR (0.38) | KDM4EHTTHPGDALDH1A1KMT2A | |
| SCHEMBL12703780 | 0.71 | TSHR (0.38) | KDM4EHTTHPGDALDH1A1KMT2A | |
| SCHEMBL15609918 | 0.71 | ALDH1A1 (0.38) | KDM4EHTTPDE3BPDE3AHPGD | |
| SCHEMBL3070590 | 0.70 | KDM4E (0.37) | KDM4EHTTPDE3BPDE3AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888597-A2 | ANTIBACTERIAL AGENTS | Warner-Lambert Company LLC (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006120563-A2 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2006-11-16 | — | — | WO | disclosed |