Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 7/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 7/20 | 0.36 |
| ▸ | WNT1 | P04628 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | ERN1 | O75460 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAK | O14976 | 2/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5011046 | 0.83 | KDM4E (0.34) | KDM4EHTTALDH1A1GAAL3MBTL1 | |
| SCHEMBL5012158 | 0.83 | KDM4E (0.34) | KDM4EHTTALDH1A1GAAL3MBTL1 | |
| SCHEMBL5011042 | 0.83 | KDM4E (0.34) | KDM4EHTTALDH1A1GAAL3MBTL1 | |
| SCHEMBL5014296 | 0.80 | KDM4E (0.33) | KDM4EHTTALDH1A1 | |
| SCHEMBL3069764 | 0.79 | KDM4E (0.34) | KDM4EHTT | |
| SCHEMBL3065399 | 0.79 | KDM4E (0.34) | KDM4EHTT | |
| SCHEMBL2216534 | 0.79 | GSK3B (0.36) | GSK3BDYRK1AWNT1ALDH1A1CYP1A2 | |
| SCHEMBL5012250 | 0.79 | GAK (0.32) | KDM4EHTTGAK | |
| SCHEMBL5012155 | 0.78 | KDM4E (0.34) | KDM4EHTTPDE3BPDE3AALDH1A1 | |
| SCHEMBL2258284 | 0.75 | L3MBTL1 (0.36) | KDM4EHTTALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888597-A2 | ANTIBACTERIAL AGENTS | Warner-Lambert Company LLC (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006120563-A2 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2006-11-16 | — | — | WO | disclosed |