Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6938579 | 1.00 | TDP1 (0.41) | TDP1LMNATSHRHPGDHSD17B10 | |
| Acetone SCHEMBL2176182 | 0.96 | LMNA (0.41) | TDP1LMNATSHRHPGDHSD17B10 | |
| SCHEMBL23567079 | 0.86 | ALDH1A1 (0.41) | LMNATSHRHPGDHSD17B10ALOX15 | |
| SCHEMBL5035198 | 0.85 | TSHR (0.39) | TSHRHPGDNPC1RAB9AALDH1A1 | |
| SCHEMBL6057627 | 0.82 | HPGD (0.43) | TDP1LMNATSHRHPGDHSD17B10 | |
| SCHEMBL5963748 | 0.82 | TDP1 (0.43) | TDP1LMNATSHRHPGDHSD17B10 | |
| SCHEMBL10873868 | 0.82 | NPC1 (0.31) | NPC1RAB9ACA12CA1CA2 | |
| SCHEMBL16271188 | 0.82 | TSHR (0.47) | TDP1LMNATSHRNPC1RAB9A | |
| SCHEMBL21798546 | 0.82 | TSHR (0.47) | TDP1LMNATSHRNPC1RAB9A | |
| SCHEMBL2355030 | 0.82 | TSHR (0.47) | TDP1LMNATSHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7348453-B2 | Labile linkage for compound delivery to a cell | MIRUS BIO CORPORATION (US) | 2008-03-25 | — | — | US | disclosed |
| US-20050054604-A1 | Labile linkage for compound delivery to a cell | ROCHE MADISON INC. | 2005-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050054604-A1 | Labile linkage for compound delivery to a cell | AADAC, PAICS, FURIN | TDP1 3103/4885LMNA 1044/4885TSHR 4180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.