SCHEMBL5012296

SCHEMBL5012296

CCCCc1ccc(-c2cc(Nc3ccc(C(C)C)cc3)ccc2-c2ccc(-c3ccc(Nc4ccc(C(C)C)cc4)cc3)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
UCHL3 P15374 2/20 0.44
MAPT P10636 3/20 0.39
SMN1; SMN2 Q16637 4/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
HPGD P15428 3/20 0.39
GAA P10253 2/20 0.39
MAPK1 P28482 2/20 0.39
LMNA P02545 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39
ALOX12 P18054 1/20 0.39
KMT2A Q03164 1/20 0.39
AKR1C2 P52895 1/20 0.38
AKR1C1 Q04828 1/20 0.38
RARB P10826 2/20 0.38
TP53 P04637 1/20 0.37
XBP1 P17861 1/20 0.37
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5617645 0.85 APP (0.42) MAPTSMN1; SMN2NPC1RAB9AHPGD
SCHEMBL29977076 0.84 TRPV1 (0.46) MAPTSMN1; SMN2NPC1RAB9AHPGD
SCHEMBL9898781 0.84 TRPV1 (0.46) MAPTSMN1; SMN2NPC1RAB9AHPGD
SCHEMBL4823761 0.82 HPGD (0.39) MAPTSMN1; SMN2NPC1RAB9AHPGD
SCHEMBL3990792 0.81 TRPV1 (0.46) MAPTSMN1; SMN2NPC1RAB9AHPGD
SCHEMBL2207287 0.81 NPSR1 (0.45) MAPTSMN1; SMN2NPC1RAB9AHPGD
SCHEMBL1726974 0.81 TRPV1 (0.43) MAPTSMN1; SMN2NPC1RAB9AHPGD
SCHEMBL3669327 0.80 UCHL3 (0.60) UCHL3MAPTHPGDMEN1ALDH1A1
SCHEMBL9875584 0.79 HTR2A (0.50) UCHL3MAPTSMN1; SMN2RAB9AHPGD
SCHEMBL13133431 0.78 RARB (0.55) MAPTSMN1; SMN2NPC1RAB9AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7419750-B2 Imaging member having antistatic anticurl back coating XEROX CORPORATION (US) 2008-09-02 US disclosed