Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31650159 | 0.89 | SMN1; SMN2 (0.77) | SMN1; SMN2TRPV4POLBTSHRMAPK1 | |
| SCHEMBL4188145 | 0.89 | SMN1; SMN2 (0.77) | SMN1; SMN2TRPV4POLBTSHRMAPK1 | |
| SCHEMBL11440887 | 0.87 | SMN1; SMN2 (0.54) | SMN1; SMN2TRPV4POLBTSHRMAPK1 | |
| SCHEMBL10800863 | 0.87 | SMN1; SMN2 (0.54) | SMN1; SMN2TRPV4POLBTSHRMAPK1 | |
| SCHEMBL4192386 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2TRPV4POLBTSHRMAPK1 | |
| SCHEMBL66188 | 0.84 | TSHR (0.70) | SMN1; SMN2POLBTSHRMAPK1ALDH1A1 | |
| SCHEMBL18969789 | 0.83 | TSHR (0.54) | SMN1; SMN2TRPV4POLBTSHRMAPK1 | |
| SCHEMBL4201928 | 0.83 | SMN1; SMN2 (0.50) | SMN1; SMN2TRPV4POLBTSHRMAPK1 | |
| SCHEMBL4192390 | 0.83 | SMN1; SMN2 (0.50) | SMN1; SMN2TRPV4POLBTSHRMAPK1 | |
| SCHEMBL4618678 | 0.83 | HTR6 (0.58) | SMN1; SMN2TRPV4POLBTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008129288-A2 | DISULFONAMIDES USEFUL IN THE TREATMENT OF INFLAMMATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-10-30 | — | — | WO | disclosed |
| US-6670474-B2 | Such as bis-1,2-(2-(2,3-epoxypropyl)phenoxy)ethane; chemical intermediates for formation of epoxy resins | PEWS R GARTH (US) | 2003-12-30 | — | — | US | disclosed |
| US-20020151731-A1 | Novel epoxide derivatives of allylarylphenols | PEWS R GARTH (US) | 2002-10-17 | — | — | US | disclosed |
| US-4945169-A | Novel bis-maleimide compounds containing sulfonate linkages | INDSPEC CHEMICAL CORPORATION (US) | 1990-07-31 | — | — | US | disclosed |
| US-4438245-A | FOR LIGHT SENSITIVE ELEMENTS | FUJI PHOTO FILM CO., LTD. (JP) | 1984-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020151731-A1 | Novel epoxide derivatives of allylarylphenols | EPHX2, CBR3, CYP4X1 | SMN1; SMN2 4841/4885TRPV4 793/4885POLB 2231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.