Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 9/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11497305 | 0.87 | PKM (0.60) | SMN1; SMN2PTGS2PTGS1CA1CA2 | |
| SCHEMBL5012595 | 0.87 | SMN1; SMN2 (0.59) | SMN1; SMN2CA1CA2TRPV4GAA | |
| SCHEMBL31650159 | 0.84 | SMN1; SMN2 (0.77) | SMN1; SMN2PTGS2PTGS1TRPV4POLB | |
| SCHEMBL4188145 | 0.84 | SMN1; SMN2 (0.77) | SMN1; SMN2PTGS2PTGS1TRPV4POLB | |
| SCHEMBL10800863 | 0.83 | SMN1; SMN2 (0.54) | SMN1; SMN2PTGS2TRPV4POLBTSHR | |
| SCHEMBL4192386 | 0.80 | SMN1; SMN2 (0.51) | SMN1; SMN2TRPV4POLBTSHRMAPK1 | |
| SCHEMBL2007287 | 0.80 | POLB (0.70) | SMN1; SMN2PTGS2PTGS1CA1CA2 | |
| SCHEMBL4618678 | 0.79 | HTR6 (0.58) | SMN1; SMN2CA9CA12TRPV4GAA | |
| SCHEMBL18969789 | 0.79 | TSHR (0.54) | SMN1; SMN2TRPV4GAAPKMPOLB | |
| SCHEMBL4192390 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2TRPV4POLBTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4211776-A | ANTIEMETICS | CHOAY S.A. (FR) | 1980-07-08 | — | — | US | disclosed |
| US-4132786-A | ANTIEMETICS, ANTICONVULSANTS, ANESTHETICS, ANTIBIOTICS | MOREAU ROBERT C | 1979-01-02 | — | — | US | disclosed |