Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 3/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9187411 | 0.87 | — | — | |
| SCHEMBL10451241 | 0.86 | CYP1A2 (0.41) | CES2CES1EPHX1HPGDKMT2A | |
| SCHEMBL3434822 | 0.84 | EPHX1 (0.38) | CES2CES1EPHX1HPGDKMT2A | |
| SCHEMBL27478468 | 0.81 | KMT2A (0.41) | CES2CES1EPHX1HPGDKMT2A | |
| SCHEMBL16168275 | 0.81 | EPHX1 (0.41) | CES2CES1EPHX1HPGDKMT2A | |
| Thiophene SCHEMBL28743390 | 0.80 | EPHX2 (0.39) | CES2CES1EPHX1HPGDKMT2A | |
| SCHEMBL19189959 | 0.80 | SMN1; SMN2 (0.47) | EPHX1HPGDKMT2AALDH1A1EPHX2 | |
| Thiophene SCHEMBL27521434 | 0.80 | EPHX2 (0.39) | CES2CES1EPHX1HPGDKMT2A | |
| Thiophene SCHEMBL27520151 | 0.80 | EPHX2 (0.39) | CES2CES1EPHX1HPGDKMT2A | |
| SCHEMBL3435663 | 0.79 | EPHX1 (0.37) | EPHX1HPGDKMT2AALDH1A1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023069720-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-04-27 | — | — | WO | disclosed |
| US-20080113994-A1 | Annelated Quinoline Derivatives As Pesticide | VELTEN ROBERT | 2008-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080113994-A1 | Annelated Quinoline Derivatives As Pesticide | DDT, ACHE, SIRT4 | CES2 771/4885CES1 1393/4885EPHX1 2819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.