Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Alanine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 1/20 | 0.48 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.48 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.48 |
| ▸ | GABRP | O00591 | 2/20 | 0.39 |
| ▸ | GABRD | O14764 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.39 |
| ▸ | GABRE | P78334 | 2/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alanine SCHEMBL11693939 | 1.00 | GLRA1 (0.48) | GLRA1SLC6A9OR51E2GABRPGABRD | |
| Alanine SCHEMBL17513685 | 0.90 | GLRA1 (0.59) | GLRA1SLC6A9OR51E2GABRPGABRD | |
| Alanine SCHEMBL186137 | 0.90 | GLRA1 (0.59) | GLRA1SLC6A9OR51E2GABRPGABRD | |
| D-Alanine SCHEMBL1537294 | 0.90 | GLRA1 (0.59) | GLRA1SLC6A9OR51E2GABRPGABRD | |
| Alanine SCHEMBL1675385 | 0.90 | GLRA1 (0.59) | GLRA1SLC6A9OR51E2GABRPGABRD | |
| Alanine SCHEMBL25189736 | 0.90 | GLRA1 (0.59) | GLRA1SLC6A9OR51E2GABRPGABRD | |
| Alanine SCHEMBL8383645 | 0.90 | GLRA1 (0.59) | GLRA1SLC6A9OR51E2GABRPGABRD | |
| Alanine SCHEMBL819876 | 0.90 | GLRA1 (0.59) | GLRA1SLC6A9OR51E2GABRPGABRD | |
| Alanine SCHEMBL2083490 | 0.90 | GLRA1 (0.59) | GLRA1SLC6A9OR51E2GABRPGABRD | |
| Alanine SCHEMBL6534719 | 0.90 | GLRA1 (0.59) | GLRA1SLC6A9OR51E2GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4019084-A | Pyroelectric vidicon having a protective covering on the pyroelectric target | NORTH AMERICAN PHILIPS CORPORATION (US) | 1977-04-19 | — | — | US | claimed |
| CN-113720796-A | Logging gas analysis system, method, equipment and medium based on infrared spectroscopy | 中国石油天然气集团有限公司 | 2021-11-30 | — | — | CN | disclosed |
| CN-110383131-B | Beam splitter assembly | 株式会社岛津制作所 | 2021-10-26 | — | — | CN | disclosed |
| CN-111505786-B | Beam splitter module and analyzer having the same | 株式会社岛津制作所 | 2021-10-22 | — | — | CN | disclosed |
| US-11086134-B2 | Beam splitter assembly | SHIMADZU CORPORATION (JP) | 2021-08-10 | — | — | US | disclosed |
| CN-111505786-A | Beam splitter module and analyzer having the same | 株式会社岛津制作所 | 2020-08-07 | — | — | CN | disclosed |
| US-20200249413-A1 | Beam Splitter Assembly and Analyzer Including the Same | SHIMADZU CORPORATION (JP) | 2020-08-06 | — | — | US | disclosed |
| US-20200159033-A1 | BEAM SPLITTER ASSEMBLY | SHIMADZU CORPORATION (JP) | 2020-05-21 | — | — | US | disclosed |
| CN-110383131-A | Beam splitter component | 株式会社岛津制作所 | 2019-10-25 | — | — | CN | disclosed |
| CN-109946261-A | Adjustable THz wave detection device of absorbing wavelength and preparation method thereof | 中国科学院深圳先进技术研究院 | 2019-06-28 | — | — | CN | disclosed |
| CN-103852439-A | Volatile organic compound monitoring equipment and method | BEIJING SDL TECHNOLOGY CO LTD | 2014-06-11 | — | — | CN | disclosed |
| US-8129683-B2 | Waveform information acquisition apparatus and waveform information acquisition method | CANON KABUSHIKI KAISHA (JP) | 2012-03-06 | — | — | US | disclosed |
| US-20100258727-A1 | WAVEFORM INFORMATION ACQUISITION APPARATUS AND WAVEFORM INFORMATION ACQUISITION METHOD | CANON KABUSHIKI KAISHA (JP) | 2010-10-14 | — | — | US | disclosed |
| WO-2009084712-A1 | WAVEFORM INFORMATION ACQUISITION APPARATUS AND METHOD | CANON KABUSHIKI KAISHA (JP) | 2009-07-09 | — | — | WO | disclosed |
| US-4019084-A | Pyroelectric vidicon having a protective covering on the pyroelectric target | NORTH AMERICAN PHILIPS CORPORATION (US) | 1977-04-19 | — | — | US | disclosed |
| US-3999698-A | Method of sealing a pyroelectric target in a vacuum tight envelope | NORTH AMERICAN PHILIPS CORPORATION (US) | 1976-12-28 | — | — | US | disclosed |