SCHEMBL5012804

SCHEMBL5012804

CCOC(=NS(=O)(=O)c1cccc(C)c1C#N)NC(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
TBXA2R P21731 4/20 0.35
BRAF P15056 1/20 0.35
KMT2A Q03164 1/20 0.34
FNTA P49354 4/20 0.33
FNTB P49356 4/20 0.33
MAPK1 P28482 3/20 0.32
KAT7 O95251 1/20 0.32
KAT6B Q8WYB5 1/20 0.32
KAT6A Q92794 1/20 0.32
KAT5 Q92993 1/20 0.32
KAT8 Q9H7Z6 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5012802 1.00 LMNA (0.38) LMNACYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL13994230 1.00 LMNA (0.38) LMNACYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL13994242 0.85 CYP3A4 (0.38) LMNACYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL2428796 0.82 CYP1A2 (0.40) LMNACYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL5007590 0.78 F2 (0.40) LMNACYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL5007599 0.76 F2 (0.39) LMNACYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL5007593 0.76 F2 (0.39) LMNACYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL5009632 0.71 CYP1A2 (0.36) LMNACYP1A2CYP2C19KMT2ASMN1; SMN2
SCHEMBL5009630 0.71 CYP1A2 (0.36) LMNACYP1A2CYP2C19KMT2ASMN1; SMN2
SCHEMBL13994218 0.71 LMNA (0.38) LMNATBXA2RMAPK1KAT7KAT6B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080300280-A1 Cyanobenzene Compounds for Combating Animal Pests BASF SE (DE) 2008-12-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080300280-A1 Cyanobenzene Compounds for Combating Animal Pests NR0B1, NR0B2, CBR1 LMNA 4546/4885CYP1A2 149/4885CYP3A4 668/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.