Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5014337 | 0.85 | KDM4E (0.35) | KDM4EALDH1A1RAB9AIRAK4HTT | |
| SCHEMBL5011046 | 0.83 | KDM4E (0.34) | KDM4EALDH1A1RAB9AHTTL3MBTL1 | |
| SCHEMBL5011042 | 0.83 | KDM4E (0.34) | KDM4EALDH1A1RAB9AHTTL3MBTL1 | |
| SCHEMBL5012158 | 0.83 | KDM4E (0.34) | KDM4EALDH1A1RAB9AHTTL3MBTL1 | |
| SCHEMBL5012712 | 0.83 | ALDH1A1 (0.32) | ALDH1A1RAB9A | |
| SCHEMBL5054392 | 0.81 | KDM4E (0.31) | KDM4EALDH1A1RAB9AHPGDCYP2C19 | |
| SCHEMBL5010975 | 0.81 | KDM4E (0.33) | KDM4EALDH1A1RAB9AHTT | |
| SCHEMBL5063593 | 0.81 | KDM4E (0.33) | KDM4EALDH1A1RAB9AHTT | |
| SCHEMBL5012206 | 0.81 | KDM4E (0.33) | KDM4EALDH1A1RAB9AHTT | |
| SCHEMBL5012744 | 0.81 | KDM4E (0.33) | KDM4EALDH1A1RAB9AHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888597-A2 | ANTIBACTERIAL AGENTS | Warner-Lambert Company LLC (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006120563-A2 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2006-11-16 | — | — | WO | disclosed |