SCHEMBL5013142

SCHEMBL5013142

CCCCC(=O)C(=O)c1ccco1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 4/20 0.57
CES1 P23141 4/20 0.57
HDAC3 O15379 1/20 0.53
PTPN1 P18031 1/20 0.52
GAA P10253 3/20 0.50
ALDH1A1 P00352 5/20 0.47
KMT2A Q03164 3/20 0.47
MEN1 O00255 2/20 0.47
HPGD P15428 1/20 0.47
RAB9A P51151 2/20 0.46
LMNA P02545 1/20 0.46
POLB P06746 2/20 0.45
ERCC5 P28715 1/20 0.45
FEN1 P39748 1/20 0.45
TSHR P16473 1/20 0.45
PKM P14618 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
KDM4E B2RXH2 1/20 0.43
MAPT P10636 1/20 0.43
NLRP1 Q9C000 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28189603 0.93 CES2 (0.57) CES2CES1HDAC3PTPN1GAA
SCHEMBL3507027 0.86 HDAC3 (0.55) CES2CES1HDAC3PTPN1GAA
SCHEMBL16501821 0.82 ERCC5 (0.61) CES2CES1HDAC3GAAALDH1A1
SCHEMBL9577885 0.82 CES2 (0.65) CES2CES1HDAC3PTPN1GAA
SCHEMBL1531620 0.81 GAA (0.57) CES2CES1HDAC3PTPN1GAA
SCHEMBL25222615 0.79 GAA (0.59) CES2CES1HDAC3GAAALDH1A1
SCHEMBL18825687 0.79 GAA (0.59) CES2CES1HDAC3GAAALDH1A1
SCHEMBL10353082 0.79 GAA (0.59) CES2CES1HDAC3GAAALDH1A1
SCHEMBL4373141 0.79 GAA (0.59) CES2CES1HDAC3GAAALDH1A1
SCHEMBL4382929 0.79 GAA (0.59) CES2CES1HDAC3GAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1922398-A1 CONSUMER PRODUCTS HAVING VARYING ODOR PATTERNS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-05-21 EP disclosed
WO-2007028477-A1 CONSUMER PRODUCTS HAVING VARYING ODOR PATTERNS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-03-15 WO disclosed
US-5385833-A Enzymatic synthesis of alcohols from carbonyl compounds THE SCRIPPS RESEARCH INSTITUTE (US) 1995-01-31 US disclosed