Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.65 |
| ▸ | CES1 | P23141 | 2/20 | 0.65 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.50 |
| ▸ | FEN1 | P39748 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 5/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5013142 | 0.82 | CES2 (0.57) | CES2CES1PTPN1NPC1RAB9A | |
| SCHEMBL574955 | 0.81 | — | — | |
| SCHEMBL28703859 | 0.81 | CES2 (0.61) | CES2CES1PTPN1NPC1TP53 | |
| SCHEMBL27188906 | 0.81 | CES2 (0.61) | CES2CES1PTPN1NPC1TP53 | |
| SCHEMBL15233 | 0.80 | CES2 (1.00) | CES2CES1PTPN1RAB9AERCC5 | |
| SCHEMBL2155972 | 0.80 | CES2 (1.00) | CES2CES1PTPN1RAB9AERCC5 | |
| SCHEMBL11776695 | 0.80 | CES2 (0.65) | CES2CES1PTPN1NPC1RAB9A | |
| SCHEMBL11537332 | 0.79 | CES2 (0.41) | CES2CES1PTPN1NPC1RAB9A | |
| SCHEMBL28189603 | 0.79 | CES2 (0.57) | CES2CES1PTPN1RAB9AGAA | |
| Ammonia Solution, Strong SCHEMBL11456969 | 0.78 | CES2 (0.95) | CES2CES1PTPN1RAB9AERCC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4861727-A | Luminescent oxygen sensor based on a lanthanide complex | C. R. BARD, INC. (US) | 1989-08-29 | — | — | US | claimed |
| EP-0259951-A2 | Luminescent oxygen sensor based on a lanthanide complex | C.R. BARD, INC. (US) | 1988-03-16 | — | — | EP | claimed |
| US-9770439-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-09-26 | — | — | US | disclosed |
| US-5190729-A | Luminescent oxygen sensor based on a lanthanide complex | C. R. BARD, INC. (US) | 1993-03-02 | — | — | US | disclosed |
| US-4900933-A | Excitation and detection apparatus for remote sensor connected by optical fiber | C. R. BARD, INC. (US) | 1990-02-13 | — | — | US | disclosed |
| US-4861727-A | Luminescent oxygen sensor based on a lanthanide complex | C. R. BARD, INC. (US) | 1989-08-29 | — | — | US | disclosed |
| EP-0283289-A2 | Excitation and detection apparatus for remote sensor connected by optical fiber | C.R. BARD, INC. (US) | 1988-09-21 | — | — | EP | disclosed |
| EP-0259951-A2 | Luminescent oxygen sensor based on a lanthanide complex | C.R. BARD, INC. (US) | 1988-03-16 | — | — | EP | disclosed |
| US-4143173-A | Flavoring with 5-acyl-2-(furfurylthio)dihydro-2,5-dialkyl-3-[2H]furanones | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1979-03-06 | — | — | US | disclosed |
| US-4138413-A | DIMERIZING AN A,B-DIKETONE, SULFIDING | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1979-02-06 | — | — | US | disclosed |
| US-4126708-A | FLAVORING WITH 2-ACYL-5-SUBSTITUTED THIATETRAHYDROFURAN-4-ONES | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1978-11-21 | — | — | US | disclosed |
| US-4096158-A | Process for preparing 5-acyl-2-(furfurylthio)dihydro-2,5-dialkyl-3-[2H]furanones | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1978-06-20 | — | — | US | disclosed |
| US-4092333-A | 2-Acyl-5-substituted thiatetrahydrofuran-4-ones | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1978-05-30 | — | — | US | disclosed |
| US-4092334-A | ORGANOLEPTIC PROPERTIES, FLAVOR OR AROMA MODIFIERS FOR FOOD, TOBACCO PRODUCTS, CHEWING GUM AND MEDICINALS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1978-05-30 | — | — | US | disclosed |