Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MPI | P34949 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5010802 | 0.91 | ALDH1A1 (0.41) | TNFDNMT1PTGS2ALDH1A1TSHR | |
| SCHEMBL5008784 | 0.83 | DNMT1 (0.38) | TNFDNMT1PTGS2ALDH1A1TSHR | |
| SCHEMBL5010725 | 0.80 | L3MBTL1 (0.37) | TNFDNMT1PTGS2ALDH1A1TSHR | |
| SCHEMBL5010129 | 0.74 | L3MBTL1 (0.39) | TNFALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL28364735 | 0.74 | CA12 (0.49) | TNFALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL29732781 | 0.73 | TNF (0.52) | TNFALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL623148 | 0.73 | TNF (0.52) | TNFALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL867854 | 0.73 | TNF (0.52) | TNFALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL29463735 | 0.73 | TNF (0.52) | TNFALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL24871224 | 0.73 | POLB (0.47) | TNFDNMT1ALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207864-A1 | Organosilanes, Process For Production of the Same, and Use Thereof | SHARP KABUSHIKI KAISHA (JP) | 2008-08-28 | — | — | US | disclosed |