SCHEMBL5013976

SCHEMBL5013976

Cc1cc(C(c2cc(C)cc(C(C)(C)C)c2O)C(c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.62
SMN1; SMN2 Q16637 4/20 0.62
ALDH1A1 P00352 4/20 0.62
POLB P06746 1/20 0.62
TYR P14679 1/20 0.62
HSPA5 P11021 1/20 0.47
CYP2C9 P11712 4/20 0.46
CYP2C19 P33261 4/20 0.46
HIF1A Q16665 2/20 0.46
CA1 P00915 2/20 0.44
HSD17B10 Q99714 2/20 0.41
CYP2D6 P10635 2/20 0.41
PTGS1 P23219 2/20 0.40
PTGS2 P35354 2/20 0.40
CYP1A2 P05177 3/20 0.39
MAPT P10636 2/20 0.39
ALOX15 P16050 2/20 0.39
HPN P05981 1/20 0.39
SIRT5 Q9NXA8 1/20 0.39
TSHR P16473 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1597366 0.83 CA2 (0.61) CA2SMN1; SMN2ALDH1A1POLBTYR
SCHEMBL265350 0.82 SMN1; SMN2 (0.61) CA2SMN1; SMN2ALDH1A1POLBTYR
SCHEMBL17676662 0.81 SMN1; SMN2 (0.59) CA2SMN1; SMN2ALDH1A1POLBTYR
SCHEMBL11392407 0.80 SMN1; SMN2 (0.53) CA2SMN1; SMN2ALDH1A1POLBTYR
SCHEMBL17438141 0.80 SMN1; SMN2 (0.68) CA2SMN1; SMN2ALDH1A1POLBTYR
Butylated Hydroxytoluene SCHEMBL3950 0.79 SMN1; SMN2 (1.00) CA2SMN1; SMN2ALDH1A1POLBTYR
Butylated Hydroxytoluene SCHEMBL453824 0.79 SMN1; SMN2 (1.00) CA2SMN1; SMN2ALDH1A1POLBTYR
SCHEMBL8014517 0.79 HSPA5 (0.53) CA2SMN1; SMN2ALDH1A1POLBTYR
SCHEMBL1524825 0.79 HSPA5 (0.53) CA2SMN1; SMN2ALDH1A1POLBTYR
SCHEMBL56222 0.78 CA2 (0.65) CA2SMN1; SMN2ALDH1A1POLBTYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3824051-A1 LUBRICANT GREASE COMPOSITION BASED ON SILICONE BASE STOCK DDP SPECIALTY ELECTRONIC MATERIALS US 9, LLC. (US) 2021-05-26 EP disclosed
US-20210122993-A1 THERMOPLASTIC COMPOSITION DDP SPECIALTY ELECTRONIC MAT US 9 LLC (US) 2021-04-29 US disclosed
WO-2020018286-A1 LUBRICANT GREASE COMPOSITION BASED ON SILICONE BASE STOCK DOW SILICONES CORPORATION (US) 2020-01-23 WO disclosed
US-10011801-B2 Organosiloxane compositions DOW SILICONES CORPORATION (US) 2018-07-03 US disclosed
US-20160281019-A1 ORGANOSILOXANE COMPOSITIONS DOW CORNING CORPORATION 2016-09-29 US disclosed
EP-3071678-A1 ORGANOSILOXANE COMPOSITIONS Dow Corning Corporation (US) 2016-09-28 EP disclosed
US-20150232782-A1 LUBRICANT COMPOSITIONS DOW CORNING (US) 2015-08-20 US disclosed
EP-2885383-A1 LUBRICANT COMPOSITIONS Dow Corning Corporation (US) 2015-06-24 EP disclosed
WO-2015077391-A1 ORGANOSILOXANE COMPOSITIONS DOW CORNING CORPORATION (US) 2015-05-28 WO disclosed
WO-2014028632-A1 LUBRICANT COMPOSITIONS DOW CORNING CORPORATION (US) 2014-02-20 WO disclosed
EP-1710295-A1 Tractor fluids Afton Chemical Corporation (US) 2006-10-11 EP disclosed
US-20060079412-A1 Power transmission fluids with enhanced antishudder durability and handling characteristics AFTON CHEMICAL CORPORATION 2006-04-13 US disclosed
EP-1645616-A1 Power transmission fluids with enhanced antishudder durability Afton Chemical Corporation (US) 2006-04-12 EP disclosed
US-20060025314-A1 Power transmission fluids with enhanced extreme pressure and antiwear characteristics AFTON CHEMICAL CORPORATION 2006-02-02 US disclosed
EP-1577370-A2 Power transmission fluids Afton Chemical Corporation (US) 2005-09-21 EP disclosed
US-20050202979-A1 Power transmission fluids with enhanced extreme pressure characteristics ETHYL PETROLEUM ADDITIVES, INC. 2005-09-15 US disclosed
EP-1553158-A1 Power Transmission Fluids with Enhanced Anti-Shudder Characteristics Afton Chemical Corporation (US) 2005-07-13 EP disclosed
US-20050148478-A1 Power transmission fluids with enhanced anti-shudder characteristics AFTON CHEMICAL CORPORATION 2005-07-07 US disclosed
US-6133210-A COMPOSITION COMPRISING POLYMERIC CARBOXYLIC ESTER VISCOSITY IMPROVER AND HYDROCARBYL GROUP SUBSTITUTED ASHLESS DISPERSANT THE LUBRIZOL CORPORATION (US) 2000-10-17 US disclosed
US-5578236-A HAVING SPECIFIED VISCOSITY ETHYL CORPORATION (US) 1996-11-26 US disclosed