SCHEMBL5014185

SCHEMBL5014185

CO[Si](CCCNC(=O)Oc1c[nH]cn1)(OC)OC

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
MGLL Q99685 5/20 0.34
BCHE P06276 1/20 0.33
LIPE Q05469 1/20 0.33
NPC1 O15118 1/20 0.32
GAA P10253 1/20 0.32
RAB9A P51151 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32
MTNR1A P48039 1/20 0.32
MTNR1B P49286 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL390769 0.78 SMN1; SMN2 (0.40) ALDH1A1NPC1RAB9A
SCHEMBL467687 0.72 EPHX1 (0.55) NPC1GAARAB9AMTNR1AMTNR1B
SCHEMBL7091507 0.71 NPC1 (0.57) NPC1GAARAB9ATAAR1
SCHEMBL2143933 0.71 KDM4E (0.33)
SCHEMBL15736560 0.71 RECQL (0.41) ALDH1A1MGLLNPC1GAARAB9A
SCHEMBL28299554 0.70 EPHX1 (0.53) NPC1GAARAB9AMTNR1AMTNR1B
SCHEMBL5013231 0.69 BCHE (0.42) MGLLBCHELIPENPC1GAA
SCHEMBL33524965 0.69 NPC1 (0.36) ALDH1A1NPC1RAB9A
SCHEMBL12972369 0.68 EPHX1 (0.41) NPC1GAARAB9A
SCHEMBL13978949 0.68 ACHE (0.60)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1991629-B1 HYBRID MEMBRANES, METHOD FOR THE PRODUCTION THEREOF, AND FUEL CELLS USING SUCH HYBRID MEMBRANES FREUDENBERG CARL KG (DE) 2018-11-21 EP disclosed
EP-1991629-A1 HYBRID MEMBRANES, METHOD FOR THE PRODUCTION THEREOF, AND FUEL CELLS USING SUCH HYBRID MEMBRANES Sartorius Stedim Biotech GmbH (DE) 2008-11-19 EP disclosed
WO-2007101537-A1 HYBRID MEMBRANES, METHOD FOR THE PRODUCTION THEREOF, AND FUEL CELLS USING SUCH HYBRID MEMBRANES ELCOMAX MEMBRANES GMBH (DE) 2007-09-13 WO disclosed