SCHEMBL5013231

SCHEMBL5013231

CO[Si](CCCNC(=O)Oc1ccc2[nH]cnc2c1)(OC)OC

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.42
LIPE Q05469 1/20 0.42
FAAH O00519 3/20 0.41
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
MMP12 P39900 1/20 0.40
KMT2A Q03164 1/20 0.40
TRPV1 Q8NER1 1/20 0.39
EPHX1 P07099 1/20 0.39
MGLL Q99685 1/20 0.39
POLB P06746 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
GAA P10253 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6422804 0.89 BCHE (0.41) BCHELIPEEPHX1MGLL
SCHEMBL6422284 0.84 ACHE (0.47) BCHELIPEEPHX1MGLL
SCHEMBL396107 0.81 POLB (0.53) NPC1RAB9AKMT2APOLBTDP1
SCHEMBL4606421 0.76 MMP12 (0.47) NPC1RAB9AMMP12KMT2APOLB
SCHEMBL4603903 0.75 ALDH1A1 (0.41) NPC1RAB9AMMP12KMT2APOLB
SCHEMBL396108 0.74 HTT (0.65) NPC1RAB9AKMT2APOLBTDP1
SCHEMBL7091507 0.73 NPC1 (0.57) FAAHNPC1RAB9AGAATAAR1
SCHEMBL1875326 0.73 MMP12 (0.46) NPC1RAB9AMMP12KMT2AGAA
SCHEMBL30138396 0.72 HTR1A (0.48) NPC1RAB9AMMP12KMT2A
SCHEMBL30799777 0.72 KMT2A (0.54) NPC1RAB9AMMP12KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1991629-B1 HYBRID MEMBRANES, METHOD FOR THE PRODUCTION THEREOF, AND FUEL CELLS USING SUCH HYBRID MEMBRANES FREUDENBERG CARL KG (DE) 2018-11-21 EP disclosed
EP-1991629-A1 HYBRID MEMBRANES, METHOD FOR THE PRODUCTION THEREOF, AND FUEL CELLS USING SUCH HYBRID MEMBRANES Sartorius Stedim Biotech GmbH (DE) 2008-11-19 EP disclosed
WO-2007101537-A1 HYBRID MEMBRANES, METHOD FOR THE PRODUCTION THEREOF, AND FUEL CELLS USING SUCH HYBRID MEMBRANES ELCOMAX MEMBRANES GMBH (DE) 2007-09-13 WO disclosed