Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | C3AR1 | Q16581 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 11/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5062951 | 0.91 | MAPT (0.49) | MAPTC3AR1MEN1KMT2AALDH1A1 | |
| SCHEMBL10045814 | 0.81 | MAPT (0.69) | MAPTMEN1KMT2ATDP1POLB | |
| SCHEMBL5015675 | 0.79 | MAPT (0.59) | MAPTC3AR1MEN1KMT2AALDH1A1 | |
| SCHEMBL12980652 | 0.79 | C3AR1 (0.49) | MAPTC3AR1MEN1KMT2AALDH1A1 | |
| SCHEMBL16602128 | 0.79 | C3AR1 (0.49) | MAPTC3AR1MEN1KMT2AALDH1A1 | |
| SCHEMBL800900 | 0.79 | MEN1 (0.46) | MAPTC3AR1MEN1KMT2ATDP1 | |
| SCHEMBL7723269 | 0.77 | MAPT (0.48) | MAPTC3AR1MEN1KMT2AALDH1A1 | |
| SCHEMBL5014051 | 0.74 | ALDH1A1 (0.58) | MAPTC3AR1MEN1KMT2AALDH1A1 | |
| SCHEMBL10045813 | 0.74 | MAPT (0.67) | MAPTMEN1KMT2ATDP1POLB | |
| SCHEMBL10045820 | 0.74 | MAPT (0.61) | MAPTMEN1KMT2ATDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009942-A1 | HETEROAROMATIC-BASED PEPTIDE MACROCYCLES AS G-QUADRUPLEX LIGANDS | CAMBRIDGE ENTERPRISE LTD. (GB) | 2008-01-24 | — | — | WO | disclosed |