Sugi Predict

Sugi Predict / Compounds / SCHEMBL5014197

SCHEMBL5014197

SCHEMBL5014197

C[Si](C)(C)C#Cc1c2ccccc2cc2ccccc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 5/20 0.38
▸ CYP1B1 Q16678 2/20 0.38
▸ CYP1A1 P04798 1/20 0.38
▸ ALDH1A1 P00352 4/20 0.37
▸ HSD17B10 Q99714 3/20 0.37
▸ HIF1A Q16665 1/20 0.37
▸ HTR2A P28223 1/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.36
▸ CYP2A6 P11509 1/20 0.36
▸ HPGD P15428 3/20 0.36
▸ GLA P06280 2/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ CYP2C19 P33261 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ MAPT P10636 2/20 0.35
▸ POLB P06746 1/20 0.35
▸ PKM P14618 1/20 0.35
▸ RAD52 P43351 1/20 0.35
▸ TAAR1 Q96RJ0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL656268 0.87 ELANE (0.37) CYP1A2CYP1B1CYP1A1ALDH1A1HSD17B10
SCHEMBL14514096 0.86 ELANE (0.39) CYP1A2CYP1B1CYP1A1ALDH1A1HSD17B10
SCHEMBL652147 0.86 ELANE (0.41) CYP1A2CYP1B1CYP1A1ALDH1A1HSD17B10
SCHEMBL1470735 0.85 ALDH1A1 (0.35) CYP1A2ALDH1A1HSD17B10HPGDKDM4E
SCHEMBL29690232 0.85 ALDH1A1 (0.35) CYP1A2ALDH1A1HSD17B10HPGDKDM4E
SCHEMBL25574907 0.82 CYP1A2 (0.36) CYP1A2CYP1B1CYP1A1ALDH1A1HSD17B10
SCHEMBL14165957 0.80 ALDH1A1 (0.48) CYP1A2CYP1B1CYP1A1ALDH1A1HSD17B10
SCHEMBL26259251 0.79 CYP1A2 (0.47) CYP1A2CYP1B1CYP1A1ALDH1A1HSD17B10
SCHEMBL28270454 0.79 ALDH1A1 (0.38) CYP1A2CYP1B1CYP1A1ALDH1A1HSD17B10
SCHEMBL9473040 0.79 ALDH1A1 (0.34) CYP1A2CYP1B1CYP1A1ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111040204-B Force-induced response dynamic polymer and application thereof 厦门天策材料科技有限公司 2023-01-24 — — CN disclosed
CN-111040110-B Force-induced response dynamic polymer and application thereof 厦门天策材料科技有限公司 2022-03-11 — — CN disclosed
CN-111378169-A Force-induced response hybrid crosslinked dynamic polymer 翁秋梅 2020-07-07 — — CN disclosed
CN-111378137-A Force-induced responsive polymer with multi-network structure 翁秋梅 2020-07-07 — — CN disclosed
CN-111171365-A Force-responsive polymer foam composite material 翁秋梅 2020-05-19 — — CN disclosed
CN-111171364-A Force-responsive polymer foam particle and preparation method thereof 翁秋梅 2020-05-19 — — CN disclosed
CN-111040204-A Force-induced response dynamic polymer and application thereof 翁秋梅 2020-04-21 — — CN disclosed
CN-111040110-A Force-induced response dynamic polymer and application thereof 翁秋梅 2020-04-21 — — CN disclosed
EP-1389626-B1 Aromatic copolymers of pyrroles and an electroluminescent element using the same KOREA INST SCI & TECH (KR) 2008-12-31 — — EP disclosed
US-6780950-B2 Pyrrole compounds, polymers thereof and EL element using the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2004-08-24 — — US disclosed
US-20040034189-A1 Pyrrole compounds, polymers thereof and EL element using the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY 2004-02-19 — — US disclosed
EP-1389626-A1 Aromatic copolymers of pyrroles and an electroluminescent element using the same Korea Institute of Science and Technology (KR) 2004-02-18 — — EP disclosed
US-6395907-B1 Preparation of polyaromatic-ethynyl thermal setting agents VIRGINIA COMMONWEALTH UNIVERSITY 2002-05-28 — — US disclosed