Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GAK | O14976 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2306871 | 1.00 | TSHR (0.41) | TSHRKDM4ELMNAHTTMAPT | |
| SCHEMBL2305986 | 1.00 | TSHR (0.41) | TSHRKDM4ELMNAHTTMAPT | |
| SCHEMBL2310386 | 0.86 | TSHR (0.45) | TSHRKDM4ELMNAHTTMAPT | |
| SCHEMBL2211812 | 0.76 | ALDH1A1 (0.46) | TSHRKDM4ELMNAMAPTALDH1A1 | |
| SCHEMBL3751398 | 0.75 | KDM4E (0.40) | TSHRKDM4EHTTMAPTALDH1A1 | |
| SCHEMBL4706251 | 0.75 | KDM4E (0.43) | TSHRKDM4EHTTMAPTALDH1A1 | |
| SCHEMBL2357083 | 0.75 | KDM4E (0.40) | TSHRKDM4EHTTMAPTALDH1A1 | |
| SCHEMBL2306361 | 0.75 | KDM4E (0.40) | TSHRKDM4EHTTMAPTALDH1A1 | |
| SCHEMBL3073265 | 0.73 | KDM4E (0.38) | TSHRKDM4ELMNAHTTMAPT | |
| SCHEMBL3069796 | 0.73 | KDM4E (0.38) | TSHRKDM4ELMNAHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888597-A2 | ANTIBACTERIAL AGENTS | Warner-Lambert Company LLC (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006120563-A2 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2006-11-16 | — | — | WO | disclosed |