Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3069796 | 0.87 | KDM4E (0.38) | KDM4EHTTMAPTALDH1A1NPSR1 | |
| SCHEMBL2309750 | 0.85 | TSHR (0.38) | KDM4EHTTMAPTALDH1A1NPSR1 | |
| Hydrochloric Acid SCHEMBL5012175 | 0.84 | MAPT (0.34) | KDM4EHTTMAPTTSHR | |
| SCHEMBL5014295 | 0.84 | TSHR (0.37) | KDM4EHTTALDH1A1NPSR1HPGD | |
| SCHEMBL2307645 | 0.81 | TSHR (0.36) | KDM4EHTTALDH1A1NPSR1HPGD | |
| SCHEMBL2305888 | 0.81 | ALDH1A1 (0.45) | KDM4EMAPTALDH1A1NPSR1HPGD | |
| SCHEMBL3653239 | 0.80 | KDM4E (0.33) | KDM4EHTTALDH1A1NPSR1TSHR | |
| SCHEMBL3066491 | 0.77 | KDM4E (0.36) | KDM4EHTTMAPTALDH1A1NPSR1 | |
| SCHEMBL3701209 | 0.76 | KDM4E (0.36) | KDM4EHTTMAPTALDH1A1NPSR1 | |
| SCHEMBL2309754 | 0.76 | KDM4E (0.36) | KDM4EHTTMAPTALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888597-A2 | ANTIBACTERIAL AGENTS | Warner-Lambert Company LLC (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006120563-A2 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2006-11-16 | — | — | WO | disclosed |