Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5014318 | 0.82 | CYP2D6 (0.37) | CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL1086977 | 0.81 | TSHR (0.39) | CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL17304528 | 0.81 | TSHR (0.39) | CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL17680158 | 0.79 | CYP2D6 (0.38) | CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL17678860 | 0.77 | TSHR (0.39) | CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL2022933 | 0.76 | CYP2D6 (0.35) | CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL9245665 | 0.76 | TSHR (0.42) | CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL14498333 | 0.75 | CYP2D6 (0.38) | CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL7144350 | 0.75 | CYP2D6 (0.38) | CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL14498331 | 0.75 | CYP2D6 (0.38) | CYP2D6TSHRCYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1319008-B1 | WATER SOLUBLE RAPAMYCIN ESTERS | WYETH CORP (US) | 2008-10-15 | — | — | EP | claimed |