Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GALR3 | O60755 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12563069 | 0.92 | CYP2D6 (0.34) | TSHRCYP2D6CYP2C19HIF1AALDH1A1 | |
| SCHEMBL1114434 | 0.89 | TSHR (0.44) | TSHRCYP2D6CYP2C19HIF1AALDH1A1 | |
| Hydrochloric Acid SCHEMBL7654212 | 0.86 | TSHR (0.42) | TSHRCYP2D6CYP2C19HIF1AALDH1A1 | |
| SCHEMBL11938747 | 0.84 | ALDH1A1 (0.39) | TSHRALDH1A1LMNAHSD17B10GALR3 | |
| SCHEMBL1086977 | 0.83 | TSHR (0.39) | TSHRCYP2D6CYP2C19HIF1AALDH1A1 | |
| SCHEMBL13038934 | 0.83 | ALDH1A1 (0.42) | TSHRCYP2D6CYP2C19HIF1AALDH1A1 | |
| SCHEMBL17680158 | 0.81 | CYP2D6 (0.38) | TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL5014370 | 0.81 | CYP2D6 (0.38) | TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL9139867 | 0.81 | TSHR (0.38) | TSHRCYP2D6CYP2C19HIF1AALDH1A1 | |
| SCHEMBL15581002 | 0.81 | KDM4E (0.36) | TSHRALDH1A1LMNAHSD17B10GALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9399044-B2 | Antimicrobial cationic polyamines | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2016-07-26 | — | — | US | disclosed |
| US-20150342984-A1 | ANTIMICROBIAL CATIONIC POLYAMINES | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2015-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150342984-A1 | ANTIMICROBIAL CATIONIC POLYAMINES | ARG1, PARG, ARG2 | TSHR 701/4885CYP2D6 4796/4885CYP2C19 3871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.