SCHEMBL1086977

SCHEMBL1086977

CC(CO)(COC(=O)C(C)(CO)CO)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C19 P33261 1/20 0.39
HIF1A Q16665 1/20 0.39
PRKCA P17252 1/20 0.33
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17680158 0.98 CYP2D6 (0.38) TSHRCYP2D6CYP2C19HIF1APRKCA
SCHEMBL17678860 0.96 TSHR (0.39) TSHRCYP2D6CYP2C19HIF1APRKCA
SCHEMBL14498332 0.94 CYP2D6 (0.38) TSHRCYP2D6CYP2C19HIF1APRKCA
SCHEMBL14498333 0.94 CYP2D6 (0.38) TSHRCYP2D6CYP2C19HIF1APRKCA
SCHEMBL14498331 0.94 CYP2D6 (0.38) TSHRCYP2D6CYP2C19HIF1APRKCA
SCHEMBL7144350 0.94 CYP2D6 (0.38) TSHRCYP2D6CYP2C19HIF1APRKCA
SCHEMBL17069742 0.92 CYP2D6 (0.37) TSHRCYP2D6CYP2C19HIF1APRKCA
SCHEMBL14498334 0.88 CYP2D6 (0.34) TSHRCYP2D6CYP2C19HIF1APRKCA
SCHEMBL2022933 0.86 CYP2D6 (0.35) TSHRCYP2D6CYP2C19HIF1APRKCA
SCHEMBL23095205 0.83 DGAT1 (0.35) PRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10947347-B2 Hyrophilic ethylene oxide free emulsifier comprising dendrimeric polyhydroxylated ester moieties MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2021-03-16 US disclosed
US-9498973-B2 Ink jet recording system SEIKO EPSON CORPORATION (JP) 2016-11-22 US disclosed
US-20160102179-A1 HYROPHILIC ETHYLENE OXIDE FREE EMULSIFIER COMPRISING DENDRIMERIC POLYHYDROXYLATED ESTER MOIETIES CITIBANK, N.A., AS ADMINISTRATIVE AGENT 2016-04-14 US disclosed
US-20160016402-A1 INK JET RECORDING SYSTEM SEIKO EPSON CORPORATION (JP) 2016-01-21 US disclosed
US-20120097194-A1 Polymeric Coatings Incorporating Bioactive Enzymes for Catalytic Function REACTIVE SURFACES, LTD. (US) 2012-04-26 US disclosed
US-8153708-B2 Process for forming a waterborne composite polyurethane/acrylic polymer dispersion PPG INDUSTRIES OHIO, INC (US) 2012-04-10 US disclosed
US-20110250626-A1 Visual Assays for Coatings Incorporating Bioactive Enzymes for Catalytic Functions REACTIVE SURFACES, LTD. (US) 2011-10-13 US disclosed
US-20110240064-A1 Polymeric Coatings Incorporating Bioactive Enzymes for Cleaning a Surface REACTIVE SURFACES, LTD. (US) 2011-10-06 US disclosed
US-20110245415-A1 PROCESS FOR FORMING A WATERBORNE COMPOSITE POLYURETHANE/ACRYLIC POLYMER DISPERSION PPG INDUSTRIES OHIO, INC. (US) 2011-10-06 US disclosed
US-8008416-B2 Curable alkoxycarbonylamino compositions, coatings, and methods BASF COATINGS GMBH (DE) 2011-08-30 US disclosed
EP-2324087-A2 COATINGS AND SURFACE TREATMENTS HAVING ACTIVE ENZYMES AND PEPTIDES McDaniel, Steven C. (US) 2011-05-25 EP disclosed
US-20110083884-A1 NOVEL POLYIMIDE PRECURSOR COMPOSITION AND USE THEREOF KANEKA CORPORATION (JP) 2011-04-14 US disclosed
US-20110061915-A1 NOVEL RESIN COMPOSITION AND USE THEREOF KANEKA CORPORATION (JP) 2011-03-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10947347-B2 Hyrophilic ethylene oxide free emulsifier comprising dendrimeric polyhydroxylated ester moieties HAO2, PAOX, ELOVL1 TSHR 4030/4885CYP2D6 1735/4885CYP2C19 1436/4885
US-20160102179-A1 HYROPHILIC ETHYLENE OXIDE FREE EMULSIFIER COMPRISING DENDRIMERIC POLYHYDROXYLATED ESTER MOIETIES HAO2, PAOX, ELOVL1 TSHR 4030/4885CYP2D6 1735/4885CYP2C19 1436/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.