Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.67 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | DRD1 | P21728 | 2/20 | 0.56 |
| ▸ | DRD3 | P35462 | 2/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5177521 | 1.00 | OPRM1 (0.67) | OPRM1SLC22A1LMNAADRA1ACYP3A4 | |
| SCHEMBL9918290 | 0.90 | OPRM1 (0.66) | OPRM1SLC22A1LMNAADRA1ACYP3A4 | |
| SCHEMBL9918287 | 0.90 | OPRM1 (0.66) | OPRM1SLC22A1LMNAADRA1ACYP3A4 | |
| SCHEMBL15471672 | 0.88 | OPRM1 (0.73) | OPRM1SLC22A1LMNAADRA1ACYP3A4 | |
| SCHEMBL16871402 | 0.88 | OPRM1 (0.73) | OPRM1SLC22A1LMNAADRA1ACYP3A4 | |
| SCHEMBL18427495 | 0.85 | OPRM1 (0.56) | OPRM1SLC22A1LMNAADRA1ACYP3A4 | |
| SCHEMBL15471651 | 0.84 | OPRM1 (0.68) | OPRM1SLC22A1LMNAADRA1ACYP3A4 | |
| SCHEMBL725882 | 0.84 | OPRM1 (0.68) | OPRM1SLC22A1LMNAADRA1ACYP3A4 | |
| SCHEMBL18371747 | 0.84 | OPRM1 (0.59) | OPRM1SLC22A1LMNAADRA1ACYP3A4 | |
| SCHEMBL19313152 | 0.84 | OPRM1 (0.59) | OPRM1SLC22A1LMNAADRA1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4094994-A | ANTICANCER AGENTS, TUMOR INHIBITION, HORMONE-DEPENDENT CARCINOMAS | KLINGE PHARMA GMBH (DT) | 1978-06-13 | — | — | US | claimed |
| WO-2008002435-A1 | VISCOELASTIC FOAMS WITH SLOWER RECOVERY AND IMPROVED TEAR | BAYER MATERIALSCIENCE LLC (US) | 2008-01-03 | — | — | WO | disclosed |
| EP-1873179-A1 | Viscoelastic foams with slower recovery and improved tear | Bayer MaterialScience LLC (US) | 2008-01-02 | — | — | EP | disclosed |
| US-20070299153-A1 | Viscoelastic foams with slower recovery and improved tear | COVESTRO LLC | 2007-12-27 | — | — | US | disclosed |
| US-4094994-A | ANTICANCER AGENTS, TUMOR INHIBITION, HORMONE-DEPENDENT CARCINOMAS | KLINGE PHARMA GMBH (DT) | 1978-06-13 | — | — | US | disclosed |