Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL263810 | 0.88 | — | — | |
| SCHEMBL6261190 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL508111 | 0.85 | — | — | |
| SCHEMBL11876388 | 0.84 | — | — | |
| Sulfuric Acid SCHEMBL8648494 | 0.81 | KDM4E (0.35) | — | |
| Nitric Acid SCHEMBL7455687 | 0.77 | CA5A (0.38) | — | |
| Nitric Acid SCHEMBL241104 | 0.77 | CA5A (0.38) | — | |
| Perchlorate SCHEMBL6260971 | 0.76 | — | — | |
| SCHEMBL6261197 | 0.75 | ALDH1A1 (0.31) | — | |
| Guanidine SCHEMBL7622738 | 0.74 | CA5A (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107573203-B | A kind of cryogenic gas propellant | 湖北航天化学技术研究所 | 2019-10-11 | — | — | CN | claimed |
| CN-107573203-A | A kind of cryogenic gas propellant | 湖北航天化学技术研究所 | 2018-01-12 | — | — | CN | claimed |
| CN-105777587-A | N-nitrotrinitroethyl carbamate energetic ionic salt and preparation method and application thereof | 中国科学院上海有机化学研究所 | 2016-07-20 | — | — | CN | claimed |
| US-20080286165-A1 | Guanidine Based Composition and System for Same | GRAUPNER ROBERT K | 2008-11-20 | — | — | US | claimed |
| CN-1976874-A | Guanidine-based compositions and systems for use in such compositions | GRAUPNER ROBERT K (US) | 2007-06-06 | — | — | CN | claimed |
| EP-1742871-A2 | GUANIDINE BASED COMPOSITION AND SYSTEM FOR SAME | Graupner, Robert K. (US) | 2007-01-17 | — | — | EP | claimed |
| WO-2005108289-A2 | GUANIDINE BASED COMPOSITION AND SYSTEM FOR SAME | GRAUPNER ROBERT K (US) | 2005-11-17 | — | — | WO | claimed |
| CN-107573203-B | A kind of cryogenic gas propellant | 湖北航天化学技术研究所 | 2019-10-11 | — | — | CN | disclosed |
| CN-105777587-B | N- nitro Trinitroethyls carbamate ion salt containing energy, preparation method and application | 中国科学院上海有机化学研究所 | 2018-06-26 | — | — | CN | disclosed |
| CN-107573203-A | A kind of cryogenic gas propellant | 湖北航天化学技术研究所 | 2018-01-12 | — | — | CN | disclosed |