SCHEMBL5014894

SCHEMBL5014894

C=C(C)C(=O)OCCC[Si]1(O)CCCCO1

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
POLB P06746 1/20 0.37
APEX1 P27695 1/20 0.37
HTT P42858 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
THRB P10828 1/20 0.37
ALDH1A1 P00352 1/20 0.36
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5024468 0.93 TSHR (0.42) TSHRPOLBAPEX1HTTTDP1
SCHEMBL9073350 0.83 TSHR (0.46) TSHRPOLBAPEX1HTTTDP1
SCHEMBL27691277 0.75 TSHR (0.49) TSHRPOLBAPEX1HTTTDP1
SCHEMBL27389968 0.74 TSHR (0.49) TSHRPOLBAPEX1HTTTDP1
SCHEMBL5144090 0.73 TSHR (0.79) TSHRPOLBAPEX1HTTTDP1
SCHEMBL25426 0.73 TSHR (0.79) TSHRPOLBAPEX1HTTTDP1
SCHEMBL22023212 0.71 TSHR (0.83) TSHRPOLBAPEX1HTTTDP1
SCHEMBL22554429 0.71 TSHR (0.83) TSHRPOLBAPEX1HTTTDP1
SCHEMBL3502350 0.71 TSHR (0.83) TSHRPOLBAPEX1HTTTDP1
SCHEMBL22554406 0.71 TSHR (0.83) TSHRPOLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9115277-B2 Porous polyolefin resin film MITSUBISHI PLASTICS, INC. (JP) 2015-08-25 US disclosed
US-20130236793-A1 POROUS POLYOLEFIN RESIN FILM MITSUBISHI PLASTICS, INC. (JP) 2013-09-12 US disclosed
EP-2626380-A1 POROUS POLYOLEFIN RESIN FILM Mitsubishi Plastics, Inc. (JP) 2013-08-14 EP disclosed
US-7393911-B2 Organosilicon fine particles and method of producing same TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) 2008-07-01 US disclosed
US-20060089478-A1 antireflection and antiblocking characteristics to synthetic polymer films and sheets when applied to their surface or caused to be contained, respectively, and adherence and slip characteristics to a skin care cosmetic material when caused to be contained TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) 2006-04-27 US disclosed