Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5014894 | 0.83 | TSHR (0.46) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL7533258 | 0.81 | TSHR (0.49) | TSHRTHRBALDH1A1 | |
| SCHEMBL5028821 | 0.78 | TSHR (0.41) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL5024468 | 0.78 | TSHR (0.42) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL27691277 | 0.78 | TSHR (0.49) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL14559770 | 0.78 | TSHR (0.34) | TSHR | |
| SCHEMBL27389968 | 0.77 | TSHR (0.49) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL12349771 | 0.73 | TSHR (0.44) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL15682455 | 0.73 | TSHR (0.54) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL17460853 | 0.73 | TSHR (0.54) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532302-A | Flame retardant composition and method for use in synthetic thermoplastic resins | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5306558-A | Double-layered rubber laminate | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1994-04-26 | — | — | US | disclosed |
| US-4987180-A | SOFTNESS, ELASTIC RESILIENCE, WINDPROOFING, WASHFASTNESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| US-4985155-A | Graft Polymer of an Acrylate on a Polysiloxane | NISSIN CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |