SCHEMBL5014941

SCHEMBL5014941

CCCCCCCCCCCCc1ccc2c(C(N)=O)c(O)ccc2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KAT8 Q9H7Z6 3/20 0.53
PPARA Q07869 1/20 0.50
EP300 Q09472 1/20 0.45
KAT5 Q92993 1/20 0.45
ESR1 P03372 2/20 0.43
ADRA2A P08913 2/20 0.43
ADORA3 P0DMS8 2/20 0.43
TACR2 P21452 2/20 0.43
SLC6A2 P23975 2/20 0.43
SLC6A4 P31645 2/20 0.43
SLC6A3 Q01959 2/20 0.43
HSD17B10 Q99714 2/20 0.43
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
LMNA P02545 1/20 0.43
SHBG P04278 1/20 0.43
TP53 P04637 1/20 0.43
CYP3A4 P08684 1/20 0.43
HSPD1 P10809 1/20 0.43
ADRB3 P13945 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5015956 0.84 PPARA (0.53) PPARACYP3A4
SCHEMBL7157453 0.82 KAT8 (0.45) KAT8PPARAEP300KAT5ESR1
SCHEMBL5015897 0.82 TRPV1 (0.47) KAT8PPARAPTGS2TRPV1
SCHEMBL5016274 0.82 TRPV1 (0.47) KAT8PPARAPTGS2TRPV1
SCHEMBL5016692 0.82 TRPV1 (0.47) KAT8PPARAPTGS2TRPV1
SCHEMBL6559330 0.80 KAT8 (0.54) KAT8PPARAESR1ADRA2AADORA3
SCHEMBL27661495 0.80 KAT8 (0.55) KAT8PPARAEP300KAT5ALDH1A1
SCHEMBL14232569 0.79 KAT8 (0.52) KAT8PPARAESR1ADRA2AADORA3
SCHEMBL11727912 0.77 KAT8 (0.75) KAT8PPARAESR1ADRA2AADORA3
SCHEMBL27640988 0.77 PPARA (0.44) KAT8PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7449608-B2 Naphthol derivative and charge control agent comprising the same UENO FINE CHEMICALS INDUSTRY, LTD. (JP) 2008-11-11 US disclosed
US-20050119487-A1 Naphthol derivative and charge control agent comprising the same KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 2005-06-02 US disclosed
EP-1462440-A1 NAPHTHOL DERIVATIVE AND CHARGE CONTROL AGENT COMPRISING THE SAME Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 2004-09-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050119487-A1 Naphthol derivative and charge control agent comprising the same CECR2, PEF1, NAP1L1 KAT8 782/4885PPARA 1369/4885EP300 377/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.