Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | TACR2 | P21452 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SHBG | P04278 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15292280 | 0.87 | ESR1 (0.48) | PTGS2ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL14232569 | 0.86 | KAT8 (0.52) | KAT8PTGS2ESR1ADRA2AADORA3 | |
| SCHEMBL14687958 | 0.82 | ESR1 (0.48) | KAT8PTGS2ESR1ADRA2AADORA3 | |
| SCHEMBL14613741 | 0.81 | KAT8 (0.50) | KAT8PTGS2ESR1ADRA2AADORA3 | |
| SCHEMBL5677501 | 0.81 | NPC1 (0.49) | KAT8LCKPPARAIGF1RALOX15 | |
| SCHEMBL5014941 | 0.80 | KAT8 (0.53) | KAT8PTGS2ESR1ADRA2AADORA3 | |
| SCHEMBL3156677 | 0.80 | KAT8 (0.59) | KAT8PTGS2ESR1ADRA2AADORA3 | |
| SCHEMBL22750715 | 0.80 | ERN1 (0.56) | KAT8PPARA | |
| SCHEMBL5540359 | 0.79 | KAT8 (0.48) | KAT8PTGS2ESR1ADRA2AADORA3 | |
| SCHEMBL11690859 | 0.79 | PTGS2 (0.57) | KAT8PTGS2ESR1ADRA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1038877-B1 | Binaphthol monophosphoric acid derivative and its use | TOSOH CORP (JP) | 2004-03-10 | — | — | EP | disclosed |
| US-6274745-B1 | CATALYST | TOSOH CORPORATION (JP) | 2001-08-14 | — | — | US | disclosed |
| EP-1038877-A1 | Binaphthol monophosphoric acid derivative and its use | Tosoh Corporation (JP) | 2000-09-27 | — | — | EP | disclosed |