Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP4 | P49662 | 1/20 | 0.47 |
| ▸ | CASP5 | P51878 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5015038 | 0.89 | RAB9A (0.50) | RAB9AMEN1KMT2ANPC1CASP1 | |
| SCHEMBL5063385 | 0.86 | RAB9A (0.67) | RAB9AMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL2094261 | 0.83 | RPS6KB1 (0.44) | RAB9AMEN1KMT2ANPC1PANK3 | |
| SCHEMBL5013361 | 0.81 | MEN1 (0.52) | RAB9AMEN1KMT2ANPC1PANK3 | |
| SCHEMBL2096584 | 0.77 | SCD (0.46) | RAB9ANPC1SMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL5063380 | 0.75 | RAB9A (0.67) | RAB9AMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL2091153 | 0.73 | SMN1; SMN2 (0.68) | RAB9ANPC1PPARGKDM4EALDH1A1 | |
| SCHEMBL2094258 | 0.72 | RPS6KB1 (0.44) | RAB9ANPC1PANK3SMN1; SMN2L3MBTL1 | |
| SCHEMBL10219646 | 0.72 | PPARD (0.62) | RAB9AMEN1KMT2ANPC1PPARG | |
| SCHEMBL10219602 | 0.72 | PPARD (0.65) | RAB9AMEN1KMT2ANPC1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |