Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.67 |
| ▸ | NPC1 | O15118 | 6/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5063385 | 0.88 | RAB9A (0.67) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL5013359 | 0.87 | MEN1 (0.52) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL5015038 | 0.86 | RAB9A (0.50) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL5015098 | 0.84 | SIGMAR1 (0.50) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL2095137 | 0.81 | MAPT (0.48) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL7760900 | 0.80 | RAB9A (1.00) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL5015014 | 0.80 | MAPT (0.43) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL13159141 | 0.79 | RAB9A (0.68) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL2091149 | 0.78 | SMN1; SMN2 (0.68) | RAB9ANPC1MAPTLMNAALDH1A1 | |
| SCHEMBL5015059 | 0.76 | SMN1; SMN2 (0.51) | RAB9ANPC1MAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |