Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.35 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17785090 | 1.00 | CYP2D6 (0.35) | CYP2D6SPHK1LMNAGMNNPOLB | |
| SCHEMBL27460742 | 0.78 | GPR84 (0.44) | SPHK1LMNAGRIK1SLC1A3SLC1A2 | |
| SCHEMBL1719662 | 0.76 | CYP2D6 (0.48) | CYP2D6SPHK1LMNAGMNNPOLB | |
| SCHEMBL2484739 | 0.76 | CYP2D6 (0.48) | CYP2D6SPHK1LMNAGMNNPOLB | |
| SCHEMBL289173 | 0.75 | — | — | |
| Ammonia Solution, Strong SCHEMBL17695275 | 0.74 | CYP2D6 (0.46) | CYP2D6SPHK1LMNAGMNNPOLB | |
| SCHEMBL14753958 | 0.74 | — | — | |
| SCHEMBL4208579 | 0.74 | — | — | |
| SCHEMBL1132673 | 0.72 | — | — | |
| SCHEMBL11669917 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1639080-A4 | A LIBRARY OF PHYLOGENETICALLY RELATED SEQUENCES | COGNETIX INC (US) | 2008-10-01 | — | — | EP | disclosed |
| EP-1639080-A2 | A LIBRARY OF PHYLOGENETICALLY RELATED SEQUENCES | Cognetix, Inc. (US) | 2006-03-29 | — | — | EP | disclosed |
| WO-2004108901-A2 | A LIBRARY OF PHYLOGENETICALLY RELATED SEQUENCES | COGNETIX, INC. (US) | 2004-12-16 | — | — | WO | disclosed |
| US-20040248189-A1 | Method of making a library of phylogenetically related sequences | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-12-09 | — | — | US | disclosed |