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Sugi Predict / Compounds / Ammonia Solution, Strong

Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL5015316

CCCCCc1ccccc1.N

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KCNH2 Q12809 2/20 0.66
▸ SIGMAR1 Q99720 3/20 0.61
▸ HTR2A P28223 2/20 0.56
▸ MAOA P21397 1/20 0.56
▸ ADRA2A P08913 3/20 0.56
▸ SLC6A2 P23975 3/20 0.56
▸ SLC6A4 P31645 3/20 0.56
▸ SLC6A3 Q01959 3/20 0.56
▸ ESR1 P03372 2/20 0.56
▸ ADORA3 P0DMS8 2/20 0.56
▸ TACR2 P21452 2/20 0.56
▸ L3MBTL1 Q9Y468 2/20 0.56
▸ ALDH1A1 P00352 2/20 0.56
▸ CHRM2 P08172 2/20 0.56
▸ CHRM1 P11229 2/20 0.56
▸ KDM4E B2RXH2 1/20 0.56
▸ LMNA P02545 1/20 0.56
▸ SHBG P04278 1/20 0.56
▸ TP53 P04637 1/20 0.56
▸ CYP3A4 P08684 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL378901 0.98 KCNH2 (0.69) KCNH2SIGMAR1HTR2AMAOAADRA2A
Ammonia Solution, Strong SCHEMBL28794197 0.98 KCNH2 (0.69) KCNH2SIGMAR1HTR2AMAOAADRA2A
Ammonia Solution, Strong SCHEMBL11051525 0.98 KCNH2 (0.69) KCNH2SIGMAR1HTR2AMAOAADRA2A
Ammonia Solution, Strong SCHEMBL27817213 0.98 KCNH2 (0.69) KCNH2SIGMAR1HTR2AMAOAADRA2A
Ammonia Solution, Strong SCHEMBL5015322 0.98 KCNH2 (0.69) KCNH2SIGMAR1HTR2AMAOAADRA2A
Benzene SCHEMBL28151391 0.97 KCNH2 (0.68) KCNH2SIGMAR1HTR2AMAOAADRA2A
SCHEMBL35869 0.97 KCNH2 (0.68) KCNH2SIGMAR1HTR2AMAOAADRA2A
Benzene SCHEMBL28454829 0.97 KCNH2 (0.68) KCNH2SIGMAR1HTR2AMAOAADRA2A
Hydrochloric Acid SCHEMBL11851500 0.95 KCNH2 (0.67) KCNH2SIGMAR1HTR2AADRA2ASLC6A2
Hydrochloric Acid SCHEMBL11841227 0.95 KCNH2 (0.67) KCNH2SIGMAR1HTR2AADRA2ASLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105272936-B A kind of nitrogen aryl benzothiazoles PARP inhibitor and its preparation method and application 中国科学院上海药物研究所 2019-05-17 — — CN disclosed
US-20080268374-A1 Photosensitive Composition, Pattern Forming Material, Photosensitive Laminate, Pattern Forming Apparatus, and Pattern Forming Process FUJIFILM CORPORATION (JP) 2008-10-30 — — US disclosed
CN-101107565-A Pattern forming material, pattern forming apparatus and permanent pattern forming method FUJI PHOTO FILM CO LTD (JP) 2008-01-16 — — CN disclosed
EP-1780599-A1 PHOTOSENSITIVE COMPOSITION, PATTERN FORMING MATERIAL, PHOTOSENSITIVE LAMINATE, PATTERN FORMING APPARATUS AND METHOD OF PATTERN FORMATION FUJIFILM Corporation (JP) 2007-05-02 — — EP disclosed
US-7078406-B2 Substituted diphenyloxazoles, the synthesis thereof, and the use thereof as fluorescence probes JOHNSON & JOHNSON PHARMACEUTICAL RESEARCH & DEVELOPMENT, L.L.C. (US) 2006-07-18 — — US disclosed
US-20040248851-A1 Substituted diphenyloxazoles, the synthesis thereof, and the use thereof as fluorescence probes Life Technologies Corporation 2004-12-09 — — US disclosed
US-6815445-B2 FOR USE AS FLUORESCENCE DYES AND PROBES Life Technologies Corporation 2004-11-09 — — US disclosed
EP-1442027-A1 SUBSTITUTED DIPHENYLOXAZOLES, THE SYNTHESIS THEREOF, AND THE USE THEREOF AS FLUORESCENCE PROBES 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 2004-08-04 — — EP disclosed
US-20030105111-A1 Substituted diphenyloxazoles, the synthesis thereof, and the use thereof as fluorescence probes 3-DIMENSIONAL PHARMACEUTICALS, INC. 2003-06-05 — — US disclosed
WO-2003031419-A1 SUBSTITUTED DIPHENYLOXAZOLES, THE SYNTHESIS THEREOF, AND THE USE THEREOF AS FLUORESCENCE PROBES 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 2003-04-17 — — WO disclosed
US-5767088-A USEFUL FOR TREATING PAIN, INFLAMMATION, SMOOTH MUSCLE CONTRACTION AND INDUCING VASODILATION WARNER-LAMBERT COMPANY (US) 1998-06-16 — — US disclosed
US-5650263-A Photopolymerizable composition, color filter, and production of color filter FUJI PHOTO FILM CO., LTD. (JP) 1997-07-22 — — US disclosed
US-5610145-A CARBAMATE STEREOISOMERS WARNER-LAMBERT COMPANY (US) 1997-03-11 — — US disclosed
EP-0755404-A1 TACHYKININ ANTAGONISTS WARNER-LAMBERT COMPANY (US) 1997-01-29 — — EP disclosed
US-5514502-A STYRENE-MALEIC ANHYDRIDE MODIFIED WITH AMINE FUJI PHOTO FILM CO., LTD. (JP) 1996-05-07 — — US disclosed
WO-1995028418-A2 TACHYKININ ANTAGONISTS WARNER-LAMBERT COMPANY (US) 1995-10-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040248851-A1 Substituted diphenyloxazoles, the synthesis thereof, and the use thereof as fluorescence probes DHFR, FPR1, CYP1A1 KCNH2 3759/4885SIGMAR1 1287/4885HTR2A 2034/4885
US-20030105111-A1 Substituted diphenyloxazoles, the synthesis thereof, and the use thereof as fluorescence probes DHFR, FPR1, CYP1A1 KCNH2 3759/4885SIGMAR1 1287/4885HTR2A 2034/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.